Clinical Outcome of Laparoscopic Colorectal Resection after Neoadjuvant Chemo-Radiotherapy for Colorectal Carcinoma
negm, S., nour, H., mohamed, A., zaitoun, M. (2021). Clinical Outcome of Laparoscopic Colorectal Resection after Neoadjuvant Chemo-Radiotherapy for Colorectal Carcinoma. EKB Journal Management System, 27(2), 316-323. doi: 10.21608/zumj.2019.14996.1403
said mohamed negm; Hazem nour; Ahmed shafik mohamed; Mohamed abdallah zaitoun. "Clinical Outcome of Laparoscopic Colorectal Resection after Neoadjuvant Chemo-Radiotherapy for Colorectal Carcinoma". EKB Journal Management System, 27, 2, 2021, 316-323. doi: 10.21608/zumj.2019.14996.1403
negm, S., nour, H., mohamed, A., zaitoun, M. (2021). 'Clinical Outcome of Laparoscopic Colorectal Resection after Neoadjuvant Chemo-Radiotherapy for Colorectal Carcinoma', EKB Journal Management System, 27(2), pp. 316-323. doi: 10.21608/zumj.2019.14996.1403
negm, S., nour, H., mohamed, A., zaitoun, M. Clinical Outcome of Laparoscopic Colorectal Resection after Neoadjuvant Chemo-Radiotherapy for Colorectal Carcinoma. EKB Journal Management System, 2021; 27(2): 316-323. doi: 10.21608/zumj.2019.14996.1403

Clinical Outcome of Laparoscopic Colorectal Resection after Neoadjuvant Chemo-Radiotherapy for Colorectal Carcinoma

Zagazig University Medical Journal
Article 220, Volume 27, Issue 2, March 2021, Page 316-323  XML PDF (471.19 K)
Document Type: Original Article
DOI: 10.21608/zumj.2019.14996.1403
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Authors
said mohamed negm email 1; Hazem nour2; Ahmed shafik mohamed3; Mohamed abdallah zaitoun4
1general surgery department , faculty of medicine , zagazig university
2General surgery department - Zagazig university
3Faculty of Medicine, Zagazig University, Egypt
4faculty of medicine , zagazig university
Abstract
Abstract:
Introduction :Neoadjuvant chemo-radiotherapy has the advantages of decrease local recurrence rate , deceasing toxicity , down_staging the tumor and minimize rate of mobidity .
Methods: Patients were divided into 2 groups in accordance type of preoperative Therapy ,Group 1: included 30 patients comprised those who had colorectal carcinoma with laparoscopic intervention without neoadjuvant therapy,Group 2: included 30 patients comprised those who had colorectal carcinoma with laparoscopic intervention with neoadjuvant therapy, This study included patients with colorectal carcinoma were admitted to Zagazig University Hospital & Gastrointestinal surgery center ( Mansoura university). Cases were collected in the period from December 2016 to April 2018.
Results: the results showed that there are significant differences between laparoscopic colectomy with neoadjuvant chemo-radiotheropy and those without neoadjuvant therapy in cases of rectal carcinoma while in cases of colon cancer there are no significant differences . laparoscopic colectomy has more advantages than open surgery in early ambulation , decrease time in staying in hospital , early return to work .

Conclusion: Laparoscopic colorectal resection after neoadjuvant chemo-radiotherapy has higher conversion rate & longer duration of surgery.Mortality & morbidity are equal in both groups

Keywords: Laparoscopic Colectomy, neoadjuvant therapy, Cancer Colon.
Keywords
Laparoscopic Colectomy; neoadjuvant therapy; Cancer Colon
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