Effect of Diabetic Retinopathy on Retinal Nerve Fiber Layer Thickness
Abdelmoneim, M., Elamin, A., Sadaka, A., Husein, H. (2019). Effect of Diabetic Retinopathy on Retinal Nerve Fiber Layer Thickness. EKB Journal Management System, 77(2), 5002-5007. doi: 10.21608/ejhm.2019.48507
Mohamed Tarek Abdelmoneim; Abdulla Mohamed Elamin; Alaa Abdelmongy Sadaka; Hossam Abdelfattah Husein. "Effect of Diabetic Retinopathy on Retinal Nerve Fiber Layer Thickness". EKB Journal Management System, 77, 2, 2019, 5002-5007. doi: 10.21608/ejhm.2019.48507
Abdelmoneim, M., Elamin, A., Sadaka, A., Husein, H. (2019). 'Effect of Diabetic Retinopathy on Retinal Nerve Fiber Layer Thickness', EKB Journal Management System, 77(2), pp. 5002-5007. doi: 10.21608/ejhm.2019.48507
Abdelmoneim, M., Elamin, A., Sadaka, A., Husein, H. Effect of Diabetic Retinopathy on Retinal Nerve Fiber Layer Thickness. EKB Journal Management System, 2019; 77(2): 5002-5007. doi: 10.21608/ejhm.2019.48507

Effect of Diabetic Retinopathy on Retinal Nerve Fiber Layer Thickness

The Egyptian Journal of Hospital Medicine
Article 20, Volume 77, Issue 2, October 2019, Page 5002-5007  XML PDF (531.26 K)
Document Type: Original Article
DOI: 10.21608/ejhm.2019.48507
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Authors
Mohamed Tarek Abdelmoneim; Abdulla Mohamed Elamin; Alaa Abdelmongy Sadaka; Hossam Abdelfattah Husein email
Department of Ophthalmology, Faculty of Medicine Aswan University
Abstract
Background: Diabetic retinopathy is one of the most common causes of vision loss in developed countries. Objective: The objective of this study was to assess the effect of diabetic retinopathy (DR) on the retinal nerve fiber layer (RNFL) thickness. Patients and methods: This study was carried out on 55 eyes of 35 patients designed as a prospective, interventional case series at Sohag Hospital from January, 2016 to December, 2016. A complete ophthalmologic examination was performed including best-corrected visual acuity (BCVA) using the ETDRS charts, intraocular pressure (IOP) measurement, slit-lamp biomicroscopic examination, fundus examination and fluorescein angiography. Results: The RNFL (inferior and total) thickness at each follow-up was increased significantly from baseline to 1 month and 6 months post-PRP then decreased significantly from 1 month to 6 months follow up (p < 0.001). The superior RNFL was increased significantly from baseline to 1 month post-PRP and then decreased at 6 month follow up (p < 0.001). While no significant change from 1 month to 6 months follow up (p > 0.05). Conclusion: Increase in the macular Ganglion cell (GC) thickness and RNFL at 1 month of follow-up that may be related to laser induced intraretinal inflammation which triggers increased capillary permeability and ensuing axonal edema due to the cytokine release.
Keywords
diabetic retinopathy; Retinal nerve fiber layer thickness
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