EVALUATION OF THE SCHISTOSOMICIDAL ACTIVITY OF Ficus carica AND Olea europaea LEAVES EXTRACT ON ADULT Schistosoma mansoni WORMS USING WORM KILLING ASSAY in vitro | ||||
| Journal of Animal and Poultry Production | ||||
| Article 5, Volume 7, Issue 3, March 2016, Page 113-119 PDF (253.38 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/jappmu.2016.48524 | ||||
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| Authors | ||||
| Enayat S. Reda1; Eman A. El-Shabasy1; Sahar M. Hamed2; A. H. Sahib1 | ||||
| 1Zoology Department, Faculty of Science, Mansoura University, Mansoura, Egypt. | ||||
| 2Urology & Nephrology Center, Mansoura Universit | ||||
| Abstract | ||||
| Those exhibit contemplate investigated the possibility schistosomicidal action from claiming both Ficus carica Furthermore Olea eurpoaea abandons extracts utilizing those schistosoma mansoni worm slaughtering test in vitro. Distinctive focuses from every extricate were used; they were 25, 50, 100 What's more 200 µg/ml. Eight worms were incubated for each extracts centralization for five days. An additional eight might have been utilized Toward including that's only the tip of the iceberg extricate focuses i. E. 400 What's more 800µg/ ml incubated best for person day. Praziquantel (PZQ) dealt with worms were utilized Similarly as sure control. Phytochemical screening of both extracts might have been conveyed out to identify extracts major compound constituents answerable for action. The comes about uncovered that the F.carica extricate indicated higher flavenoid fight over O. europaea extricate (63. 6, 23. 1 µg/g respectively) same time O. europaea extricate recorded higher phenolic fight over F. caica extricate (82. 5, 56. 7µg/ g respectively). Both extracts have proliferation in vitro anti-schistosomal movement. Those resultsindicated that variable rates for worm murdering exercises (10%-100%) fluctuating as stated by those measurements about both plant extracts and the span of the extricate brooding. The worm murdering exercises reveals to An profoundly critical build with those increment for both extracts expanded (P< 0. 0001). The LC50 and LC90 about both extracts might have been 21. 35 Also 43. 35 µg/ ml separately to fig Furthermore 47. 98 Furthermore 115. 9 individually to olive then afterward five days for brooding contrasted with 48. 21 Furthermore 52. 54 µg/ml for PZQ. Olive extracts reveals to All the more schistosomicidel exercises done bring down extracts focuses. These exercises turn into equals done more broodeng the long haul. With helter skelter extricate fixation those exercises about both extracts arrived at of the PZQ level Actually then afterward special case day from claiming brooding | ||||
| Keywords | ||||
| Schistosomicidel; plant extract; Ficus carca; Olea euroaea; Worm Killing Assay; in vitro study | ||||
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