Optical Coherence Tomography Evaluation of Retinal Nerve Fiber Layer and Ganglion Cell Layer Thickness before and after Argon Laser in Treatment of Diabetic Retinopathy
Abdelmoneim, M., Elamin, A., Sadaka, A., Husein, H. (2019). Optical Coherence Tomography Evaluation of Retinal Nerve Fiber Layer and Ganglion Cell Layer Thickness before and after Argon Laser in Treatment of Diabetic Retinopathy. EKB Journal Management System, 77(2), 5032-5039. doi: 10.21608/ejhm.2019.48690
Mohamed Tarek Abdelmoneim; Abdulla Mohamed Elamin; Alaa Abdelmongy Sadaka; Hossam Abdelfattah Husein. "Optical Coherence Tomography Evaluation of Retinal Nerve Fiber Layer and Ganglion Cell Layer Thickness before and after Argon Laser in Treatment of Diabetic Retinopathy". EKB Journal Management System, 77, 2, 2019, 5032-5039. doi: 10.21608/ejhm.2019.48690
Abdelmoneim, M., Elamin, A., Sadaka, A., Husein, H. (2019). 'Optical Coherence Tomography Evaluation of Retinal Nerve Fiber Layer and Ganglion Cell Layer Thickness before and after Argon Laser in Treatment of Diabetic Retinopathy', EKB Journal Management System, 77(2), pp. 5032-5039. doi: 10.21608/ejhm.2019.48690
Abdelmoneim, M., Elamin, A., Sadaka, A., Husein, H. Optical Coherence Tomography Evaluation of Retinal Nerve Fiber Layer and Ganglion Cell Layer Thickness before and after Argon Laser in Treatment of Diabetic Retinopathy. EKB Journal Management System, 2019; 77(2): 5032-5039. doi: 10.21608/ejhm.2019.48690

Optical Coherence Tomography Evaluation of Retinal Nerve Fiber Layer and Ganglion Cell Layer Thickness before and after Argon Laser in Treatment of Diabetic Retinopathy

The Egyptian Journal of Hospital Medicine
Article 24, Volume 77, Issue 2, October 2019, Page 5032-5039  XML PDF (414.06 K)
Document Type: Original Article
DOI: 10.21608/ejhm.2019.48690
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Authors
Mohamed Tarek Abdelmoneim; Abdulla Mohamed Elamin; Alaa Abdelmongy Sadaka; Hossam Abdelfattah Husein email
Department of Ophthalmology, Faculty of Medicine, Aswan University
Abstract
Background: Diabetic retinopathy (DR) is one of the most common microvascular complications of diabetes with the potential to cause severe vision loss and blindness and a devastating effect on quality of life. Objective: Discuss the macular ganglion cell and retinal nerve fiber layer (RNFL) changes after laser treatment as a management of diabetic retinopathy. Patients and Methods: This study was carried out on 55 eyes of 35 patients designed as a prospective, interventional case series at Sohag Ophthalmic Diagnostic Laser Unit between January 2016 and March 2017. A complete ophthalmologic examination was performed, including best-corrected visual acuity (BCVA) using the ETDRS charts, intraocular pressure (IOP) measurement, slit-lamp biomicroscopic examination, fundus examination, fluorescein angiography, and 3D optical coherence tomography (OCT) 2000. Results: The value of RNFL (superior and total) in the GRID group is more than in the pan-retinal photocoagulation (PRP) group which increased at 1 month post laser (not significant) then significantly decreased at 6 month follow up. The value of RNFL (inferior) in the GRID group is more than in the PRP group which significantly increased at 1 month post laser then decreased at 6 month follow up table 4. Conclusion: Significant ganglion cell (GC) and RNLF decrease at the sixth month of follow-up can be attributed to axonal loss secondary to direct or indirect effects of PRP treatment. SD OCT is a very valuable tool to document the RNFL thickness changes following the argon laser photocoagulation.
Keywords
Optical Coherence Tomography; Retinal nerve fiber layer; Argon laser in treatment; diabetic retinopathy
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