Anti-microbial and Anti-diabetic Activity of Six Seaweeds Collected from the Red Sea, Egypt | ||||
| Catrina: The International Journal of Environmental Sciences | ||||
| Article 6, Volume 19, Issue 1, September 2019, Page 55-60 PDF (300.93 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/cat.2019.49157 | ||||
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| Authors | ||||
Nehal A Osman  1; Adel A Siam2; Islam El-Manawy1; You-Jin Jeon3
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| 1Botany Department, Faculty of Science, Suez Canal University, Ismailia, Egypt | ||||
| 2Physiology Department, Faculty of Veterinary Medicine, Suez Canal University, Ismailia, Egypt | ||||
| 3Department of Marine Life Science, Jeju National University, Jeju, Republic of Korea | ||||
| Abstract | ||||
| Marine algae are a well-known source of active compounds with many biological activities. Many studies had point to the anti-microbial and anti-diabetic activity of seaweeds. Egyptian shores are rich with seaweeds, yet studies concerning their biological activity are inadequate. In the present work, the 80% methanolic extract of six seaweeds (Actinotrichia fragilis, Cystoseira myrica, Hormophysa cuneiformis, Laurencia papillosa, Sargassum cinereum, and Turbinaria turbinate) were tested for their antimicrobial activity using disc diffusion method and anti-diabetic activity using the Inhibition of α-glucosidase method. The six species were collected from Hurghada, Red Sea, Egypt during late December, 2012. The results should that the algal extracts were effective against both Gram-positive and Gram-negative bacteria when used at 2000μg/disc concentration. On Candida albicuns, both low and high concentrations showed activity. For anti-diabetic activity, H. cuneiformis was the most active species that reached to 53% inhibition of α-glucosidase at the highest concentration (1000 μg/ml) with IC50 676.9 μg/ml. In conclusion, the tested seaweeds possess a good anti-microbial and anti-diabetic activity, especially the species Hormophysa cuneiformis. | ||||
| Keywords | ||||
| seaweed; Hormophysa cuneiformis; Actinotrichia fragilis; α-glucosidase; anti-microbial; antidiabetic | ||||
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