Inhibition of Human Breast cancer cells proliferation by Graviola crude extract | ||||
| Recent Research in Genetics and Genomics | ||||
| Article 1, Volume 1, Issue 1, 2019, Page 1-7 PDF (754.27 K) | ||||
| Document Type: Original Research Articles | ||||
| DOI: 10.21608/rrgg.2019.50222 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Razan M.H Mohammed; Magda M. Noshy; Hanan R.H Mohamed 
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| Zoology Department; Faculty of science Cairo University; Giza, Egypt | ||||
| Abstract | ||||
| Rapid increases in cancer and human death cases, as well as the fatal side effects of chemotherapy, have forced the seek new safer anti-cancer drugs. Therefore, the current study was conducted to study the effect of Graviola leaf extract on the proliferation of human breast cancer (MCF-7) cell lines. MCF-7 cells were cultured and a Neutral red uptake assay was done to estimate the effect of Graviola extract on MCF-7 cells'''' proliferation. Treatment with different concentrations of Graviola leaf extract inhibited the proliferation of MCF-7 cells in a concentration-dependent manner. Conclusion: Graviola leaf extract has a promising inhibitory effect against the proliferation of MCF-7 cells. | ||||
| Keywords | ||||
| MCF-7 cells; Graviola; NR assay; proliferation; Cytotoxicity | ||||
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