Computed Tomography Versus Magnetic Resonance Imaging in Assessment of Recto-Sigmoid Cancer Local Recurrence in Patients with Elevated Carcinoembryonic Antigen
Mohsenah, H., Zidan, E., Al Smmak, A., Almola, R. (2021). Computed Tomography Versus Magnetic Resonance Imaging in Assessment of Recto-Sigmoid Cancer Local Recurrence in Patients with Elevated Carcinoembryonic Antigen. EKB Journal Management System, 27(4), 724-734. doi: 10.21608/zumj.2019.14444.1309
Hend Abd Elmageed Mohsenah; El Sayed Zidan; Ahmed Al Smmak; Ranya Almola. "Computed Tomography Versus Magnetic Resonance Imaging in Assessment of Recto-Sigmoid Cancer Local Recurrence in Patients with Elevated Carcinoembryonic Antigen". EKB Journal Management System, 27, 4, 2021, 724-734. doi: 10.21608/zumj.2019.14444.1309
Mohsenah, H., Zidan, E., Al Smmak, A., Almola, R. (2021). 'Computed Tomography Versus Magnetic Resonance Imaging in Assessment of Recto-Sigmoid Cancer Local Recurrence in Patients with Elevated Carcinoembryonic Antigen', EKB Journal Management System, 27(4), pp. 724-734. doi: 10.21608/zumj.2019.14444.1309
Mohsenah, H., Zidan, E., Al Smmak, A., Almola, R. Computed Tomography Versus Magnetic Resonance Imaging in Assessment of Recto-Sigmoid Cancer Local Recurrence in Patients with Elevated Carcinoembryonic Antigen. EKB Journal Management System, 2021; 27(4): 724-734. doi: 10.21608/zumj.2019.14444.1309

Computed Tomography Versus Magnetic Resonance Imaging in Assessment of Recto-Sigmoid Cancer Local Recurrence in Patients with Elevated Carcinoembryonic Antigen

Zagazig University Medical Journal
Article 252, Volume 27, Issue 4, July 2021, Page 724-734  XML PDF (776.46 K)
Document Type: Original Article
DOI: 10.21608/zumj.2019.14444.1309
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Authors
Hend Abd Elmageed Mohsenah email 1; El Sayed Zidan2; Ahmed Al Smmak2; Ranya Almola2
1Radiodiagnosis department, Mit-Ghamr Oncology Center, Ministry of Health,Egypt
2Radiodiagnosis department, Faculty of medicine, Zagazig university
Abstract
Background: Colorectal cancer is widely distributed. It is considered the third most common cancer worldwide. Despite performing potentially curative operations 25% to 40% develop tumor recurrence. The optimal strategy to detect recurrences at the earliest stage remains controverse. The aim of this study is to assess recto-sigmoid cancer local recurrence in patients with elevated CEA by contrast enhanced CT and contrast enhanced MRI and compare between both modalities.
Methods: This study was carried out on 24 patients who underwent surgical excision of primary recto-sigmoid cancer and under post-operative follow up with elevated CEA level. CT and MRI were done, and the results were compared.
Results: Our study included 24 their age's ranged from 23-76 years with the mean age 53 years. Twenty cases (83%) were confirmed to have recurrence while 4 cases elevated CEA levels were considered false positive. CT accuracy (79%), sensitivity (100%) and specificity (55%). These results were not as high as those of MR imaging where MRI accuracy (96%), sensitivity (100%) and specificity (91%). By using chi square test, there was no significant difference between CT and MRI in detection and assessment of locally recurrent recto sigmoid cancer patients with P value 0.3843.
Conclusion: MRI has higher specificity than CT in determining pelvic recurrence recto-sigmoid cancer in patients with elevated CEA level. It can differentiate recurrent masses from post-operative scar tissue and determine preciously the site and type of local recurrence. However, CT is mandatory in these patients as a screening modality and follow up.
Keywords
recto-sigmoid; CEA; Recurrence; CT; MRI
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