The Effects of Different Extract of LepidiumSativum on Induced Periodontitis in Dexamethasone Immunosuppressed Rats | ||||
| Al-Azhar Dental Journal for Girls | ||||
| Article 8, Volume 4, Issue 3, July 2017, Page 249-253 PDF (408.48 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/adjg.2017.5265 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| Hoda ElSayed1; Naglaa Elkilani2; Mona Farid3 | ||||
| 1(B.D.S 2006) faculty of oral and dental medicine M.U.S.T university in Ministry of Health | ||||
| 2Professor and Head of Oral Medicine, Periodontology, Radiology, and DiagnosisFaculty of Dental Medicine for Girls, Al-Azhar University-Girls Branch. | ||||
| 3Professor and Head of the Oral and Dental Biology Department and Former Dean of Faculty of Dental Medicine for Girls, Al-Azhar University-Girls Branch. | ||||
| Abstract | ||||
| Objective : The present study was designated to evaluate the effect of lepidiumsativum extract on structure and density of bone in immunosuppressed rats with induced chronic periodontitis histologically, hostometrically as well as radiodensitometric analysis by digital radiography assessment (vista scan). Materials and methods: A total 36 wistar male rats were divided randomly into 6 groups (6 rats/group). The study sample was divided into:I - Control group: in this group rats were fed with a normal diet.II-Control group with ligature: without receiving dexamethasone injection, a sub marginal cotton ligature.III-Vehicle group: in this group rats were received a weekly dose of dexamethasone for 6 weeks and received sub marginal cotton ligature (no treatment). SRP 1 (methanol group): rats were received methanol extract for 30 days, these were subjected to scaling and root planning (SRP). SRP 2 (watery group): in this group rats were subjected to (SRP). SRP 3 group submitted only to SRP and received no further treatment.Results: methanol extract has better anabolic effect on bone and regenerative on periodontal ligaments than watery extract.This could be explained by the fact that lepidiumsativum possesses anti-inflammatory, immunomodulatory properties and antioxidative activity that may resolve periodontal inflammation. | ||||
| Keywords | ||||
| immunosuppression; dexamethasone; Chronic Periodontitis; lepidiumsativum; Extract; SRP | ||||
|
Statistics Article View: 168 PDF Download: 330 |
||||
