Effects of Vitamin D on Growth Inhibition of Head and Neck Squamous Cell Carcinoma. (In vitro study) | ||||
Al-Azhar Dental Journal for Girls | ||||
Article 6, Volume 4, Issue 4, October 2017, Page 381-384 PDF (317.01 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/adjg.2017.5285 | ||||
View on SCiNiTO | ||||
Author | ||||
Heba Hussein | ||||
Oral Medicine, Diagnosis, and Periodontology Department, Faculty of Dentistry, Cairo University | ||||
Abstract | ||||
Objective: To assess the anti-cancer capacity of vitamin D in head and neck squamous cell carcinoma cell line. Materials and Methods: vitamin D cytotoxic effect and cell apoptosis effect were evaluated using Prestoblue cell viability assay and Flow Cytometry. Results: Vitamin D was found to inhibit the cell growth in a dose-dependent manner in head and neck squamous cell carcinoma JHU-29 cell line at three days’ treatment. However, it was not found to cause significant apoptosis at one day treatment. Conclusion: vitamin D inhibits the growth of head and neck squamous cell carcinoma in a dose-dependent manner. | ||||
Keywords | ||||
Head and Neck Squamous Cell; carcinoma; Vitamin D; apoptosis | ||||
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