Corneal Collagen Cross Linking With Photo-Activated Chromophore for keratitis (PACK-CXL) As AdjunctiveTherapy for Infectious Keratitis | ||||
| Zagazig University Medical Journal | ||||
| Article 259, Volume 27, Issue 4, July 2021, Page 672-680 PDF (380.65 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/zumj.2019.16429.1468 | ||||
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| Authors | ||||
Mohammed Mahdy Tawfeek  1; Khaled Gouda Ammar2; Hesham Abdelhamid Enany3; Mohamed Hassan Hosny4
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| 1Ophthalmology Department, Faculty of Medicine, Zagazig University, Zagazig, Sharqia, Egypt | ||||
| 2Ophthalmology Department, Faculty of Medicine, Zagazig University | ||||
| 3Ophthalmology department , faculty of Medicine , Zagazig University , Zagazig , Shrqia , Egypt | ||||
| 4Ophthalmology Department, Faculty of medicine, Cairo University | ||||
| Abstract | ||||
| ABSTRACT Objectives: The aim of this work is to evaluate efficacy and safety of corneal collagen cross linking as adjunctive therapy for infectious keratitis. Patients and Methods: Seventy eight (78) eyes with clinically suspected infectious keratitis were enrolled in this study. The range of age of the enrolled patients was more than or equal to 18 years. They were classified into two groups each of 39 eyes, Group A: received topical appropriate broad spectrum antimicrobial therapy alone and Group B: received combined topical appropriate conventional broad spectrum antimicrobial therapy and corneal collagen cross linking for infectious keratitis (PACK-CXL). Identification of organisms was done by lab study before treatment. Corneal healing was evaluated by corneal examination and anterior segment OCT ( AS-OCT). Results: Complete healing and resolution was observed in 76.9 % of eyes and 97.4 % of patients in groups (A & B), respectively. They showed a statistically significant difference (P | ||||
| Keywords | ||||
| Corneal cross linking; PACK-CXL; infectious keratitis | ||||
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