Safety and efficacy of the available oral anti diabetic drugs in treating type-2 diabetics during Ramadan1437(Hijri)fasting in Fayoum Governate
Mashahit, M., Abo El-seoud, S., Sayed, N., Abd El-Ghafar, N. (2018). Safety and efficacy of the available oral anti diabetic drugs in treating type-2 diabetics during Ramadan1437(Hijri)fasting in Fayoum Governate. EKB Journal Management System, 1(1), 49-67. doi: 10.21608/fumj.2018.5429
Mohamed Abd elHady Mashahit; Sally Abo El-seoud; Norhan Sayed; Noha Abd El-Ghafar. "Safety and efficacy of the available oral anti diabetic drugs in treating type-2 diabetics during Ramadan1437(Hijri)fasting in Fayoum Governate". EKB Journal Management System, 1, 1, 2018, 49-67. doi: 10.21608/fumj.2018.5429
Mashahit, M., Abo El-seoud, S., Sayed, N., Abd El-Ghafar, N. (2018). 'Safety and efficacy of the available oral anti diabetic drugs in treating type-2 diabetics during Ramadan1437(Hijri)fasting in Fayoum Governate', EKB Journal Management System, 1(1), pp. 49-67. doi: 10.21608/fumj.2018.5429
Mashahit, M., Abo El-seoud, S., Sayed, N., Abd El-Ghafar, N. Safety and efficacy of the available oral anti diabetic drugs in treating type-2 diabetics during Ramadan1437(Hijri)fasting in Fayoum Governate. EKB Journal Management System, 2018; 1(1): 49-67. doi: 10.21608/fumj.2018.5429

Safety and efficacy of the available oral anti diabetic drugs in treating type-2 diabetics during Ramadan1437(Hijri)fasting in Fayoum Governate

Fayoum University Medical Journal
Article 1, Volume 1, Issue 1, March 2018, Page 49-67  XML PDF (920.2 K)
Document Type: Full Length research Papers
DOI: 10.21608/fumj.2018.5429
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Authors
Mohamed Abd elHady Mashahit email 1; Sally Abo El-seoud2; Norhan Sayed2; Noha Abd El-Ghafar3
1Prof of internal medicin Fayoum
2Department of Internal Medicine, Faculty of Medicine, Fayoum University, Egypt
3Department of Clinical Pathology , Faculty of Medicine, Fayoum University, Egypt
Abstract
Introduction : Fasting in Ramadan is one of the five pillars of Islam. Without relevant medical advice and intervention, fasting can put patients with T2DM at an increased risk of serious complications. The aim of this study was to compare the effectiveness and safety of available oral anti diabetic drugs in treating type-2 diabetics during Ramadan fasting.
Methods : In this 16-week prospective study, data were collected up to 6 weeks before and after Ramadan fasting . Patients who had received metformin alone or with sulfonylurea (SU), DPP4-I or TZDs or any combination of the before were enrolled into the study.
Results : This study concluded that mean total HbA1c improved during Ramadan (𝑃<0.001 ) . This study also found that patients treated with SUs experienced major hypoglycemic events Similarly, a fewer patients experienced weight gain when treated with TZDs. On the contrary we found that there was no evidence of hyperglycemia or hypoglycemia in
patients using DPP4-I.
Conclusions: There are several potential benefits of fasting during Ramadan. Active glucose monitoring throughout the holy month of Ramadan enabled us to pick up more hypoglycaemic episodes .The study revealed that the preferred antidiabetic drugs during Ramadan are DPP4-I.
Keywords
DPP4 inhibitors; Hypoglycemia; sulphonylureas; Type 2 diabetes mellitus; TZDs; Metformin
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