Can Tomosynthesis Solve the Problem of Mammographically Indeterminate Breast Lesions? | ||||
| The Medical Journal of Cairo University | ||||
| Article 85, Volume 87, June, June 2019, Page 2083-2098 PDF (1.5 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/mjcu.2019.54353 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| OMNIA MOKHTAR, M.D.; SAHAR MAHMOUD, M.D.; AMR KAMAL, M.D. | ||||
| The Department of Radiology, National Cancer Institute of Cairo*, Faculty of Medicine, Beni-Suef University** and Surgery Department***, National Cancer Institute of Cairo, Egypt | ||||
| Abstract | ||||
| Abstract Background: Breast cancer in women is a major public health problem throughout the world. To reduce the morbidity and mortality associated with breast cancer, early detection becomes a very important job. Addition of breast Tomosyn-thesis to mammography examination reduced and eliminated tissue overlap especially in women with radiographically dense breast. Aim of Study: To evaluate the impact of adding Digital Breast Tomosynthesis (DBT) to Full Field Digital Mammog-raphy (FFDM) in detection, characterization and diagnosis of mammographically indeterminate breast lesions. Subjects and Methods: The study included 80 patients with 86 indeterminate findings on mammography. DBT ex-amination was done and imaging findings were evaluated before and after the use of DBT. Results: Tomosynthesis showed better diagnostic perform-ance compared to mammography. The sensitivity of Tomo-synthesis was 90%, the specificity was 91.1%, the positive predictive value of 88%, the negative predictive value was 92.7% and the diagnostic accuracy was 91%, while the sensi-tivity of mammography was 62.5%, the specificity was 59%, the positive predictive value was 52.1%, the negative predictive value was 68.8%, and the diagnostic accuracy was 60.4%. Conclusion: DBT significantly enhanced the detection and characterization of indeterminate breast lesions on digital mammography especially in the context of dense breast parenchyma. | ||||
| Keywords | ||||
| Digital mammography – Tomosynthesis – Inde-terminate breast lesions | ||||
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