Efficacy of Intravenous 3% Hypertonic Saline Compared to Mannitol 20% for Lowering Intraocular Pressure in Glaucoma Patients | ||||
| The Medical Journal of Cairo University | ||||
| Article 72, Volume 86, March, March 2018, Page 575-579 PDF (313.54 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/mjcu.2018.55209 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| MOHAMMED H.E. HAFEZ, M.D.; GIHAN M. OBAYAH, M.D.; MAHA M.I. YOUSSEF, M.D.; MOHAMMED S. MOHAMMED, M.D.; OMNIA A. MANDOR, M.Sc. | ||||
| The Departments of Anesthesia & ICU* and Ophthalmology**, Faculty of Medicine, Cairo University | ||||
| Abstract | ||||
| Abstract Background: It is essential to reduce acutely raised in-traocular pressure before surgery and mannitol has been effectively used for this purpose. Also, intraocular pressure can be decreased by hypertonic saline by pulling fluid osmot-ically from tissues to the intravascular space. Aim of Work: To evaluate efficacy of IV infusion of HTS 3% compared to mannitol 20% for decreasing IOP in glaucoma patients. Material and Methods: 30 patients undergoing glaucoma surgery under general anesthesia were randomly allocated into 2 groups. One group recieved hypertonic saline 3% (3 ml/kg) and the other group received mannitol (0.5gm/kg). Baseline IOP was measured just before infusion then measured 5, 10, 20, 30, 60, 120min after end of infusion. Results: There was statistical significant decrease in the IOP in both groups at 1 and 2 hours after infusion when collected data were compared to baseline. Conclusion: This study concluded that IV infusion of HTS 3% seemed to be effective in decreasing IOP in glaucoma patients. It might be considered as a good alternative to mannitol for this purpose. | ||||
| Keywords | ||||
| Hypertonic saline – Mannitol – IOP – Glaucoma | ||||
|
Statistics Article View: 266 PDF Download: 352 |
||||
