The Predictive Factors for Recurrence of Spontaneous Bacterial Peritonitis | ||||
Medical Journal of Viral Hepatitis | ||||
Article 5, Volume 2.2, Issue 2, March 2018, Page 25-29 PDF (128.58 K) | ||||
Document Type: Original article | ||||
DOI: 10.21608/mjvh.2018.55738 | ||||
View on SCiNiTO | ||||
Authors | ||||
Zakaria Sahar1; Mousa Nasser1; Abd EL Maksoud Mohamed1; Shabana Walaa1; Effat Narmin2; Awad Mahmoud3; Eldesoky Abd Elmohsen3; Sheta Tarek3; El-Wakeel Niveen4; Moemen Dalia4; Mikhail Nabiel5 | ||||
1Tropical Medicine dept., Mansoura Univ., Egypt. | ||||
2Clinical Pathology dept., Mansoura Univ., Egypt | ||||
3Internal Medicine dept., Mansoura Univ., Egypt. | ||||
4Microbiology and Immu-nology dept., Mansoura Univ., Egypt | ||||
5Egyptian Liver Research Institute and Hospital (ELRIH), Sherbin, El-Mansoura, Biostatistics dept., South Egypt Cancer Institute, Assiut Univ., Egypt. | ||||
Abstract | ||||
Background and objectives: Spontaneous bacterial peritonitis (SBP) is a common and critical complication of cirrhosis. The aim of this work is to find the possible predictive factors for recurrence of SBP in decompensated cirrhotic patients. Patients and methods: This study included one hundred and thirty-four cirrhotic ascitic patients who were diagnosed with SBP. The diagnosis of SBP was based on ascitic polymorphonuclear leukocytes (PMN) counts ≥250 cells/mm3. The studied patients were classified into two groups; group 1 included sixtyninth patients with recurrent SBP and group 2; included sixty-five patients with non-recurrent SPB. Results: A significant difference was found between both studied groups as regards the presence of fever, HRS (hepatorenal syndrome, the serum albumin and the ascitic fluid PMN in ascitic cirrhotic patients (P= 0.010, p= 0.001, p=0.021, p= 0.045 respectively). Furthermore, a multivariate analysis revealed that the presence of fever, hepatorenal syndrome, and increased ascitic fluid PMN represent independent variables predict the recurrence of SBP in cirrhotic ascetic patients (p= 0.001 for all). Conclusion: Our study revealed that the presence of fever, HRS, and increased PMN count in ascitic fluid were independent predictors of recurrence of SBP in cirrhotic ascetic patients.. | ||||
Keywords | ||||
SBP; Recurrence; Hypoalbuminemia; PMN count and hepatorenal syndrome (HRS) | ||||
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