IMMUNOCHEMICAL IDENTIFICATION OF Streptococcus pneumoniae 40 KDa ANTIGEN IN CEREBROSPINAL FLUID AND SERUM OF Streptococcus pneumoniae INFECTED PATIENTS
El-Morsy, E., Abou-Dobara, M., Omran, M., El-Mansoury, M., Attallah, A. (2011). IMMUNOCHEMICAL IDENTIFICATION OF Streptococcus pneumoniae 40 KDa ANTIGEN IN CEREBROSPINAL FLUID AND SERUM OF Streptococcus pneumoniae INFECTED PATIENTS. EKB Journal Management System, 2(1), 1-13. doi: 10.21608/jacb.2011.56482
E. M. El-Morsy; M. I. Abou-Dobara; M. M. Omran; M. A. El-Mansoury; A. M. Attallah. "IMMUNOCHEMICAL IDENTIFICATION OF Streptococcus pneumoniae 40 KDa ANTIGEN IN CEREBROSPINAL FLUID AND SERUM OF Streptococcus pneumoniae INFECTED PATIENTS". EKB Journal Management System, 2, 1, 2011, 1-13. doi: 10.21608/jacb.2011.56482
El-Morsy, E., Abou-Dobara, M., Omran, M., El-Mansoury, M., Attallah, A. (2011). 'IMMUNOCHEMICAL IDENTIFICATION OF Streptococcus pneumoniae 40 KDa ANTIGEN IN CEREBROSPINAL FLUID AND SERUM OF Streptococcus pneumoniae INFECTED PATIENTS', EKB Journal Management System, 2(1), pp. 1-13. doi: 10.21608/jacb.2011.56482
El-Morsy, E., Abou-Dobara, M., Omran, M., El-Mansoury, M., Attallah, A. IMMUNOCHEMICAL IDENTIFICATION OF Streptococcus pneumoniae 40 KDa ANTIGEN IN CEREBROSPINAL FLUID AND SERUM OF Streptococcus pneumoniae INFECTED PATIENTS. EKB Journal Management System, 2011; 2(1): 1-13. doi: 10.21608/jacb.2011.56482

IMMUNOCHEMICAL IDENTIFICATION OF Streptococcus pneumoniae 40 KDa ANTIGEN IN CEREBROSPINAL FLUID AND SERUM OF Streptococcus pneumoniae INFECTED PATIENTS

Journal of Agricultural Chemistry and Biotechnology
Article 1, Volume 2, Issue 1, January 2011, Page 1-13  XML PDF (524.83 K)
Document Type: Original Article
DOI: 10.21608/jacb.2011.56482
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Authors
E. M. El-Morsy1; M. I. Abou-Dobara1; M. M. Omran2; M. A. El-Mansoury2; A. M. Attallah2
1Botany Dept., Damietta, Faculty of Science, New Damietta, Egypt
2Research and Development Dept., Biotechnology Research Center, New Damietta, Egypt
Abstract
Bacterial meningitis is a major cause of death and disability in children. Streptococcus pneumoniae is one of the common causative agents of bacterial meningitis in children. The diagnosis requires an analysis of cerebrospinalfluid (CSF), this requires a lumbar puncture to confirmthe presence of inflammatory cells in the cerebrospinal fluid,to identify the infecting pathogen, and to guide antimicrobialtherapy. We have identified the 40 kDaprotein from S. pneumoniae in CSF and Serumwith no significant differences between the antigen in serum and CSF and we used Enzyme Linked Immunosorbent Assay (ELISA) in the detection of soluble pneumococcal antigen in serum and CSF samples. So; it is possible to use serum samples in the detection of the S. pneumoniae antigeninstead of CSF samples.       
Keywords
Streptococcus pneumoniae; antigen; 40-kDa
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