Red Cell Distribution Width as a Marker of Inflammation in Type 2 Diabetes Mellitus | ||||
The Medical Journal of Cairo University | ||||
Article 20, Volume 86, September, September 2018, Page 2287-2295 PDF (644.67 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/mjcu.2018.57522 | ||||
View on SCiNiTO | ||||
Authors | ||||
HANAN M. AHMED, M.D.; MOSTAFA A. HARIDI, M.D.; MANAL E. EL-DEEN, M.D.; TAGHREED G. MADANI, M.D. | ||||
The Department of Internal Medicine, Faculty of Medicine, Assiut University Hospital, Assiut, Egypt | ||||
Abstract | ||||
Abstract Background: Red Blood Cell Distribution (RDW) is recognized as a global marker of chronic inflammation. Aim of Study: To study the relation between RDW and complications in patients with type 2 diabetes mellitus and its relation to CRP. Methods: The study included 70 patients with type 2 DM and 20 healthy controls with clinical and laboratory data including HbA1c, RDW and C Reactive Protein (CRP). Results: Patient group showed 65 (92.85%) of them had macrovascular and 64 (91.42%) patients had microvascular complications. When we compared patients with macrovascular and microvascular complications to control group we found high RDW in those with vascular complications than control group (p=0.001). There was a significant difference between RDW in patients with macrovascular complications in com-parison to those without macrovascular complications (p-value=0.02). There was a significant difference between RDW in patients with nephropathy compared to those with retinop-athy. Conclusion: In our study, we confirmed a strong relation between diabetics with vascular complications and RDW. | ||||
Keywords | ||||
DM – Microvascular complication – Macrovas- cular complication – RDW – CRP | ||||
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