Evaluation of Anemia among Patients with End Stage Renal Disease on Hemodialysis in Al-Gharbia Governorate | ||||
| The Medical Journal of Cairo University | ||||
| Article 29, Volume 86, September, September 2018, Page 2349-2359 PDF (1.11 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/mjcu.2018.57557 | ||||
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| Authors | ||||
| AHMED M.A. FAHMY, M.Sc.; GAMAL F. EL-NAGGAR, M.D.; GHADA M. AL-GHAZALY, M.D.; MOHAMED A. SAAD, M.D. | ||||
| The Departments of Internal Medicine* and Clinical Pathology**, Faculty of Medicine, Tanta University, Tanta, Egypt | ||||
| Abstract | ||||
| Abstract Background: Chronic Kidney Disease (CKD) is a major health problem and its prevelence is increasing worldwide. Chronic kidney disease results in complex endocrinal and metabolic alterations. Anemia is a common complication of chronic kidney disease. There are various causes of anemia in chronic kidney disease patients on hemodialysis like mal-nutrition, infection, inflammation and hyperparathyroidism. Aim of Work: The aim of the present work is to evaluate anemia among patients with ESRD on regular hemodialysis in Al-Gharbia governorate. Patients and Methods: The study was done on 400 patients with ESRD on regular hemodialysis in more than one center for HD in Al-Gharbia governorate. All patients in this study were subjected to: History taking, full clinical examination, laboratory investigations done were intact Complete Blood Count (CBC), parathyroid hormone, serum phosphorus, ionized calcium, serum ferritin, transferrin saturation, serum albumin and C reactive protein after obtaining an informed consent. Results: There was significant negative correlation between Hb and reticulocytic count (p=0.003 *), there was significant negative correlation between Hb and PTH (p=0.001*), there was significant negative correlation between Hb and S.albumin (p=0.019*), there was significant negative correlation between Hb and CRP (p=0.011*) there was positive significant corre-lation between Hb and T.Sat. (p=0.038*), Hb showed no significant correlation with serum ferritin, ionized calcium and phosphorus. In Conclusion: Our finding suggests that many factors affect anemia in patients with ESRD on regular hemodialysis these factors include malnutrition, inflammation, iron defi-ciency and hyperparathyroidism. | ||||
| Keywords | ||||
| Chronic Kidney Disease (CKD) – Hemodialysis – Anemia – Malnutrition – Infection – Inflamma-tion – Hyperparathyroidism | ||||
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