SOFT TISSUE HEALING AROUND IMMEDIATELY PLACED DENTAL IMPLANTS AUGMENTED WITH AMNIOTIC CHORION MEMBRANE VERSUS CONNECTIVE TISSUE GRAFT (A CLINICAL AND HISTOLOGICAL STUDY)
Zayed, N., Hommos, A., Karam, S., Fahmy, R. (2018). SOFT TISSUE HEALING AROUND IMMEDIATELY PLACED DENTAL IMPLANTS AUGMENTED WITH AMNIOTIC CHORION MEMBRANE VERSUS CONNECTIVE TISSUE GRAFT (A CLINICAL AND HISTOLOGICAL STUDY). EKB Journal Management System, 43(1), 27-34. doi: 10.21608/adjalexu.2018.57592
Norai A. Zayed; Ahmed M. Hommos; Sahar SH. Karam; Rania A. Fahmy. "SOFT TISSUE HEALING AROUND IMMEDIATELY PLACED DENTAL IMPLANTS AUGMENTED WITH AMNIOTIC CHORION MEMBRANE VERSUS CONNECTIVE TISSUE GRAFT (A CLINICAL AND HISTOLOGICAL STUDY)". EKB Journal Management System, 43, 1, 2018, 27-34. doi: 10.21608/adjalexu.2018.57592
Zayed, N., Hommos, A., Karam, S., Fahmy, R. (2018). 'SOFT TISSUE HEALING AROUND IMMEDIATELY PLACED DENTAL IMPLANTS AUGMENTED WITH AMNIOTIC CHORION MEMBRANE VERSUS CONNECTIVE TISSUE GRAFT (A CLINICAL AND HISTOLOGICAL STUDY)', EKB Journal Management System, 43(1), pp. 27-34. doi: 10.21608/adjalexu.2018.57592
Zayed, N., Hommos, A., Karam, S., Fahmy, R. SOFT TISSUE HEALING AROUND IMMEDIATELY PLACED DENTAL IMPLANTS AUGMENTED WITH AMNIOTIC CHORION MEMBRANE VERSUS CONNECTIVE TISSUE GRAFT (A CLINICAL AND HISTOLOGICAL STUDY). EKB Journal Management System, 2018; 43(1): 27-34. doi: 10.21608/adjalexu.2018.57592

SOFT TISSUE HEALING AROUND IMMEDIATELY PLACED DENTAL IMPLANTS AUGMENTED WITH AMNIOTIC CHORION MEMBRANE VERSUS CONNECTIVE TISSUE GRAFT (A CLINICAL AND HISTOLOGICAL STUDY)

Alexandria Dental Journal
Article 6, Volume 43, Issue 1, April 2018, Page 27-34  XML PDF (629.79 K)
Document Type: Original Article
DOI: 10.21608/adjalexu.2018.57592
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Authors
Norai A. Zayed1; Ahmed M. Hommos2; Sahar SH. Karam3; Rania A. Fahmy4
1B.D.S. Faculty of Dentistry Pharos University and Instructor of Periodontology, Oral Medicine, Diagnosis and Radiology, Pharos University, Alexandria, Egypt.
2Professor of Periodontology, Oral Medicine, Diagnosis and Radiology, Faculty of Dentistry Alexandria University
3Professor of Oral Biology, Faculty of Dentistry Alexandria University
4Lecturer of Periodontology, Oral Medicine, Diagnosis and Radiology, Faculty of Dentistry Alexandria University
Abstract
INTRODUCTION: The Amnion Chorion Membrane (ACM) has favorable regenerative properties which facilitates its use for covering immediate dental implants. OBJECTIVES: To evaluate clinically and histologically the effect of Amnion Chorion membrane in augmenting immediately placed dental implants compared to connective tissue graft (CTG) MATERIALS AND METHODS: This study was conducted clinically on eighteen upper hopeless anterior/premolar teeth scheduled for extraction and immediate implant placement. Patients were divided into two groups: in the first group, nine immediate implants were covered with ACM, and in the second group nine immediate implants were covered with CTG. Keratinized mucosal width (KMW), keratinized mucosal thickness (KMT) and healing score were recorded for both groups at 7 , 14 , 30 and 90 days RESULTS: The KMT showed an increase by 26% in the test group while in the control group it decreased by 6.5% by the end of the study period. Regarding the healing scores both groups showed marked improvement throughout the study, lower values of healing scores were noted in the test group. Clinical results were confirmed by histological examination which revealed that oral mucosa of both groups showed parakeratinized gingival epithelium. The connective tissue of the test group showed more regularly arranged ,thick bundles. CONCLUSIONS Both treatment modalities were satisfactory but the ACM offered more positive results concerning the mucosal thickness and healing scores.
Keywords
immediate implants; ACM; connective tissue graft; soft tissue
References
  1. Hämmerle CH, Chen ST, Wilson TG Jr. Consensus statements and recommended clinical procedures regarding the placement of implants in extraction sockets. Int J Oral Maxillofac Implants. 2004;19:26-8.
  2. Wilson TG, Jr, Schenek R, Buser D, Cochran D. Implants placed in immediate extraction sites: a report of histologic and histometric analysis of human biopsies. Int J Oral Maxillofac Implants. 1998;13:333-41.
  3. Edel A. The use of a connective tissue graft for closure over an immediate implant covered with an occlusive membrane. Clin Oral Implants Res. 1995;6:60-5.
  4. Tsuda H, Rungcharassaeng K, Kan JY, Roe P, Lozada JL, Zimmerman G. Peri-implant tissue response following connective tissue and bone grafting in conjunction with immediate single-tooth replacement in the esthetic zone: A case series. Int J Oral Maxillofac Implants. 2011;26:427-36.
  5. Celletti R, Davarpanah M, Etienne D, Pecora G, Tecucianu JF, Djukanovic D, et al. Guided tissue regeneration around dental implants in immediate extraction sockets: Comparison of e-PTFE and a new titanium membrane. Int J Periodontics Restorative Dent. 1994;14:243-53.
  6. Bourne G. The foetal membranes. A review of the anatomy of normal amnion and chorion and some aspects of their function. Postgrad Med J. 1962;38:193- 201.
  7. Steinberg AD, LeBreton G, Willey R, Mukherjee S, Lipowski J. Extravascular clot formation and platelet activation on variously treated root surfaces. J Periodontol. 1986;57:516-22.
  8. Holtzclaw D, Toscano N. Amnion chorion allograft barrier: Indications and techniques update. JIACD. 2012;4:25-38.
  9. Holtzclaw DJ, Toscano NJ. Amnion–chorion allograft barrier used for guided tissue regeneration treatment of periodontal intrabony defects: A retrospective observational report. Clin Adv Periodontics. 2013;3:131- 7.
  10. Holtzclaw D, Hinze HF, Toscano N. Gingival flap attachment healing with amnion-chorion allograft membrane: A controlled, split mouth case report replication of the classic 1968 Hiatt Study. J Implant Adv Clin Dent. 2012;4:19-25. 
  11. American Society of Anesthesiologists. ASA physical status classification system. 2007. Available at: http://www. asahq.org/clinical/physicalstatus.htm.
  12. O’Leary TJ, Drake RB, Naylor JE. The plaque control record. J Periodontol. 1972;43:38.
  13. Sato N. Periodontal Surgery: a clinical atlas. 2000. 384.
  14. AL-Mashhadani AM. The clinical effect of phenytoin on oral wound. Al-Rafidain Dent J. 2012;12:165-70.
  15. Kotz S, Balakrishnan N, Read CB, Vidakovic B. Encyclopedia of statistical sciences. 2nd ed. Hoboken, N.J.: Wiley-Interscience; 2006.
  16. Kirkpatrick LA, Feeney BC. A simple guide to IBM SPSS statistics for version 20.0. Student ed. Belmont, Calif.: Wadsworth, Cengage Learning; 2013.
  17. Cooper LF, Reside GJ, Raes F, Garriga JS, Tarrida LG, Wiltfang J, et al. immediate provisionalization of dental implants placed in healed alveolar ridges and extraction sockets: a 5-year prospective evaluation. Int J Oral Maxillofac Implants 2014; 29: 709-17.
  18. Covani U, Marconcini S, Galassini G, Cornelini R, Santini S, Barone A. Connective tissue graft used as a biologic barrier to cover an immediate implant. J Periodontol. 2007;78:1644-9.
  19. Dawson A. The SAC Classification in Implant Dentistry. Berlin: Quintessence Publishing; 2009.
  20. Tsuda H, Rungcharassaeng K, Kan JY, Roe P, Lozada JL, Zimmerman G. Peri-implant tissue response following connective tissue and bone grafting in conjunction with immediate single-tooth replacement in the esthetic zone: A case series. Int J Oral Maxillofac Implants. 2011;26:427-36.
  21. Chen Z, Tortella FC, Dave JR, Marshall VS, Clarke DL, Sing G, et al. Human amnion-derived multipotent progenitor cell treatment alleviates traumatic brain injury-induced axonal degeneration. J Neurotrauma. 2009;26:1987-97.
  22. Mangano FG, Mastrangelo P, Luongo F, Blay A, Tunchel S, Mangano C. Aesthetic outcome of immediately restored single implants placed in extraction sockets and healed sites of the anterior maxilla: a retrospective study on 103 patients with 3 years of follow-up. Clin Oral Implants Res. 2017;28:272-82.
  23. Levine RA, Ganeles J, Gonzaga L, Kan JK, Randel H, Evans CD, et al. 10 Keys for Successful Esthetic-Zone Single Immediate Implants. Compend Contin Educ Dent. 2017;38:248-60.
  24. Albannaa RF, Hasouni M. Surgical Adhesive versus Silk Suture in Oral Incisions Closure; A Histopathoplogical Comparative Study on Rabbits. Germany: Lap Lambert Publishing; 2012.
  25. Samandari MH, Adibi S, Khoshzaban A, Aghazadeh S, Dihimi P, Torbaghan SS, et al. Human amniotic membrane, best healing accelerator, and the choice of bone induction for vestibuloplasty technique (an animal study). Transplant Res Risk Manage. 2011;3:1- 8.
  26. In 't Anker PS, Scherjon SA, Kleijburg-van der Keur C, de Groot-Swings GM, Claas FH, Fibbe WE, et al. Isolation of mesenchymal stem cells of fetal or maternal origin from human placenta. Stem cells. 2004;22:1338-45.
  27. Albannaa RF, Al-Dabbagh FM, Alnema MM. Histopathological evaluation of human amniotic membrane effect on early stage healing of induced defects in rabbit's oral mucosa. MDJ. 2013;10:252-8.
  28. Kesting MR, Loeffelbein DJ, Classen M, SlottaHuspenina J, Hasler RJ, Jacobsen F, et al. Repair of oronasal fistulas with human amniotic membrane in minipigs. Br J Oral Maxillofac Surg. 2010;48:131-5.
  29. Ghahroudi AA, Khorsand A, Rokn AR, Sabounchi SS, Shayesteh YS, Soolari A. Comparison of amnion allograft with connective tissue graft for root coverage procedures: a double-blind, randomized, controlled clinical trial. J Int Acad Periodontol. 2013;15:101-12.
  30. Suresh DK, Gupta A. Gingival Biotype Enhancement and Root Coverage Using Human Placental Chorion Membrane .Clin Adv Periodontics. 2013;3:237-42.
  31. Burman S, Tejwani S, Vemuganti GK, GopinathanU, Sangwan VS. Opthalmic Applications of Preserved Human Amniotic Membrane: A Review of Current Indications. Cell Tissue Bank. 2004;5:161-75.
  32. Spray JR, Black CG, Morris HF, Ochi S. The influence of bone thickness on facial marginal bone response: Stage 1 placement through stage 2 uncovering. Ann Periodontol. 2000;5:119.
  33. Chen ST, Darby IB, Reynolds EC. A prospective clincal study of non-submerged immediate implants: Clinical outcomes and esthetic results. Clin Oral Implants Res. 2007;18:552-62.
  34. Lindeboom JA, Tjiook Y, Kroon FH. Immediate placement of implants in periapical infected sites: A prospective randomized study in 50 patients. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006;101:705-10.
  35. Oates TW, Robinson M, Gunsolley JC. Surgical Therapies for the treatment of gingival recession. A Systematic Review. Ann Periodontol 2003;8:303-20.
  36. Cordioli G, Mortarino C, Chierico A, Grusovin MG, Majzoub Z. Comparison of 2 Techniques of Subepithelial Connective Tissue Graft in the Treatment of gingival Recessions. J Periodontol 2001;72:1470-6.
  37. Dr. Lewis C. Cummings, Wayne B. Kaldahl, and Edward P. Allen . Histologic Evaluation of Autogenous Connective Tissue and Acellular Dermal Matrix Grafts in Humans. Journal of Periodontology 2005 ; 76:178- 186
  38. Schroeder HE. Biological structure of the normal giniva– preface. Department of Periodontology, Faculty of Odontology, University of Lund, Malmo, Sweden and Department or Oral Structural Biology, Dental Institute, University of Zurich, Switzerland. Periodontol 2000 2012; 13: 7.
  39. Laugerette F, Gaillard D, Passilly-Degrace P, Niot I, Besnard P. Do we taste fat? Biochimie 2007; 89: 265-9.
  40. Iwata T, Yamato M, Tsuchioka H, Takagi R, Mukobata S, Washio K, et al. Periodontal regeneration with multi-layered periodontal ligament-derived cell sheets in a canine model. Biomaterials. 2009;30:2716-23.
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