COMPARATIVE STUDY BETWEEN OSSEOINTEGRATION AROUND NANOSTRUCTURE IMPLANT AND SANDBLASTED IN IMMEDIATE PLACEMENT (EXPERIMENTAL STUDY) | ||||
Alexandria Dental Journal | ||||
Article 16, Volume 43, Issue 1, April 2018, Page 94-98 PDF (672.6 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/adjalexu.2018.57604 | ||||
View on SCiNiTO | ||||
Authors | ||||
Aya F. Barakat1; Ahmed S. El-Mahallawy2; Tarek M. Aly3; Sahar K. Shafik4 | ||||
1BDS, Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Alexandria University, Egypt | ||||
2Professor of Oral and Maxillofacial Surgery, Faculty of Dentistry, Alexandria University, Egypt. | ||||
3Professor of Oral and Maxillofacial Surgery and Dean of Faculty of Dentistry, Alexandria University, Egypt | ||||
4Head of Oral Biology Department, Faculty of Dentistry, Alexandria University, Egypt | ||||
Abstract | ||||
INTRODUCTION: The quality of the implant surfaces is one of the major factors that influences wound healing at the implantation site and subsequently affects osseo-integration. OBJECTIVES: Evaluation of the osseo-integration around nano-structured dental implant and around sandblasted type histologically. MATERIALS AND METHODS: This experimental study was done on 6 healthy mongrel dogs, all dogs were healthy as documented by a veterinarian report, and kept under the same nutritional and environmental conditions in the animal house at the Physiology Department, Faculty of Medicine, Alexandria University. All dogs were divided into 2 groups: group A received nanostructured dental implant in the left side, group B received sandblasted dental implant in the right side. Afterwards the dogs were sacrificed at 3 and 6 weeks after implant insertion. RESULTS In group A the osseo integration of all implants was noted. New bone formed in direct contact with the implant surfaces and the threads. But in group B one experimental animal preserved the implant in its place while the others were displaced from the bone with fibrous tissue interface. CONCLUSIONS: There is significant increase in the bone healing around nano dental implants as opposed to sandblasted implants. | ||||
Keywords | ||||
Osseo integration; Nano dental implants; sandblasting implants; Immediate implant; Experimental study | ||||
References | ||||
1-Widmann G, Bale RJ. Accuracy in computer-aided implant surgery--a review. Int J Oral Maxillofac Implants. 2006;21:305-13.
2-Triplett RG, Frohberg U, Sykaras N, Woody RD. Implant materials, design, and surface topographies: their influence on osseointegration of dental implants. J Long Term Eff Med Implants. 2003;13:485-501.
3- Raghavendra S, Wood MC, Taylor TD. Early wound healing aroundendosseous implants: A review of literature. Int J Oral Maxillofac Implants. 2005;20:425-31.
4- Sykaras N, Iacopino AM, Marker VA, Triplett RG, Woody RD. Implant materials. A literature review. Int J Oral Maxillofacial Implants. 2000;15:675-90.
5- Sennerby L, Dasmah A, Larsson B, Iverhed M. Surfacemodified zirconia implants: A histomorphometric and removal torque study in the rabbit. Clin Implant Dent Relat Res. 2005;7(Suppl 1):S13-20.
6- Piattelli A, Piattelli M, Romasco N, Trisi P. Histochemical and laser scanning microscopy characterization of the hydroxyapatite-bone interface: an experimental study in rabbits. Int J Oral Maxillofacial Implants. 1994;9:163-8.
7- Mavrogenis AF, Dimitriou R, Parvizi J, Babis GC. Biology of implant osseointegration. J Musculoskelet Neuronal Interact. 2009;9:61-71.
8- Peterson LJ, Ellis E, Hupp JR, Tucker MR. Contemporary oral and maxillofacial surgery. 4th ed. St Louis: Mosby; 2003.
9- Lekovic V, Kenney EB, Weinlaender M. A bone regenerative approach to alveolar ridge maintenance following tooth exraction: Report of 10 cases. J Periodontal. 1997:68:563-70.
10-Albrektsson T, Branemark PI, Hansson HA, Lindstrom J. Osseointegrated titanium implants. Requirements for ensuring a long-lasting, direct bone-to-implant anchorage in man. Acta Orthop Scand. 1981;52:155-70.
11-Fan Z, Jia S, Su JS. Influence of surface roughness of titanium implant on core binding factor alpha 1 subunit of osteoblasts. Zhonghua Kou Qiang Yi Xue Za Zhi. 2010;45:466-70.
12-Jager M, Zilkens C, Zanger K, Krauspe R. Significance of nano- and microtopography for cell- surface interactions in orthopaedic implants. J Biomed Biotechnol. 2007;2007:69036.
13-Webster TJ, Schadler LS, Siegel RW, Bizios R. Mechanisms of enhanced osteoblast adhesion on nanophase alumina involve vitronectin. Tissue Eng. 2001;7:291-301.
14-Webster TJ, Ejiofor JU. Increased osteoblast adhesion on nanophase metals: Ti, Ti6A14V, and CoCrMo. Biomaterials. 2004;25:4731-9.
15-Le Guehennec L, Soueidan A, Layrolle P, Amouriq Y. Surface treatments of titanium dental implants for rapid osseointegration. Dent Mater. 2007;23:844-54.
16-De Oliveira PT, Nanci A. Nanotexturing of titanium-based surfaces upregulates expression of bone sialoprotein and osteopontin by cultured osteogenic cells. Biomaterials. 2004;25:403-13.
17-Aita H, Hori N, Takeuchi M, Suzuki T, Yamada M, Anpo M, Ogawa T. The effect of ultraviolet functionalization of titanium on integration with bone. Biomaterials. 2009;30:1015-25.
18-Saito T, Hayashi H, Kameyama T, Hishida M, Nagai K, Teraoka K, et al. Suppressed proliferation of mouse osteoblast-like cells by a rough surfaced substrate leads to low differentiation and mineralization. Mater Sci Eng C Mater Biol Appl. 2010;30:1-7.
19-Adell R, Eriksson B, Lekholm U, Branemark PI, Jemt T. Long-term follow-up study of osseointegrated implants in the treatment of totally edentulous jaws. Int J Oral Maxillofac Implants. 1990;5:347-59.
20-Bowers KT, Keller JC, Randolph BA, Wick DG, Michaels CM. Optimization of surface micromorphology for enhanced osteoblast responses in vitro. Int J Oral Maxillofac Implants. 1992; 7:302-10.
21- Martin JY, Schwartz Z, Hummert TW, Schraub DM, Simpson J, Lankford J Jr, et al. Effect of titanium surface roughness on proliferation, differentiation, and protein synthesis of human osteoblast-like cells (MG63). J Biomed Mater Res. 1995; 29:389-401.
22- Cochran DL, Schenk RK, Lussi A, Higginbottom FL, Buser D. Bone response to unloaded and loaded titanium implants with sandblasted and acid-etched surface: A histometric study in the canine mandible. J Biomed Mater Res. 1998; 40:1-11.
23- Strbac GD, Unger E, Donner R, Bijak M, Watzek G, Zechner W. Thermal effects of a combined irrigation method during implant site drilling. A standardized in vitro study using a bovine rib model. Clin Oral Implants Res. 2014; 25: 665-74.
24-Cardaropoli G, Araujo M, Lindhe J. Dynamics of bone tissue formation in tooth extraction sites. An experimental study in dogs. J Clin Periodontol. 2003;30:809–18.
25-Araujo MG, Lindhe J. Dimensional ridge alterations following tooth extraction. An experimental study in the dog. J Clin Periodontol. 2005;32:212–8.
26-Berglundh T, Abrahamsson I, Lang NP, Lindhe J. De novo alveolar bone formation adjacent to endosseous implants. Clin Oral Implants Res. 2003;14:251–62.
27-Abrahamsson I, Berglundh T, Linder E, Lang NP, Lindhe J. Early bone formation adjacent to rough and turned endosseous implant surfaces. An experimental study in the dog. Clin Oral Implants Res. 2004;15:381–92.
28- Meirelles L, Arvidsson A, Albrektsson T, Wennerberg A. Increased bone formation to unstable nano rough titanium implants. Clin Oral Implants Res. 2007;18:326– 32.
29- Meirelles L, Arvidsson A, Andersson M, Kjellin P, Albrektsson T, Wennerberg A. Nano hydroxyapatite structures influence early bone formation. J Biomed Mater Res A. 2008;87:299–307.
30- Williams D. The Williams Dictionary of Biomaterials. Liverpool: Liverpool University Press; 1999.
31-Mendes VC, Moineddin R, Davies JE. The effect of discrete calcium phosphate nanocrystals on bone-bonding to titanium surfaces. Biomaterials. 2007;28:4748–55.
32- Mendes VC, Moineddin R, Davies JE. Discrete calcium phosphate nanocrystalline deposition enhances osteoconduction on titanium-based implant surfaces. J Biomed Mater Res A. 2009;90:577-85.
33- Kim SJ, Kim MR, Rim JS, Chung SM, Shin SW. Comparison of implant stability after different implant surface treatments in dog bone. J Appl Oral Sci. 2010; 18: 415-20.
34- Ballo A, Agheli H, Lausmaa J, Thomsen P, Petronis S. Nanostructured model implants for in vivo studies: influence of well-defined nanotopography on de novo bone formation on titanium implants. Int J Nanomedicine. 2011; 6:3415-28. | ||||
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