PROTECTIVE EFFECT OF NIGELLA SATIVA OIL ON TESTICULAR MORPHO-PHYSYLOGICAL CHANGES INDUCED BY CHRONIC ALCOHOLISM IN ALBINO RATS | ||||
| The Egyptian Journal of Anatomy | ||||
| Article 7, Volume 26, Issue 2, July 2003, Page 173-194 PDF (1.22 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejana.2003.5884 | ||||
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| Authors | ||||
| Nadia EI • Rouby1; Romysa EI - Sherbeny2 | ||||
| 1Histology Department. Faculty of Medicine. Cairo University | ||||
| 2Physiology Department, Faculty of Medicine, Tanta University | ||||
| Abstract | ||||
| Alcoholism is an illness caused by consumption of alcohol beverages at a level that interferes with physical or mental health. and social. family, or occupational responsibility. People with alcohol dependence have to increase markedly amounts of alcohol to achieve intoxication or the desired effect (Thomas, 20(3). Alcoholism affects 15 1020 million Americans and affects three to four times as many family members. coworkers. and friends, It is involved in half of all fatal automobile accidents and is responsible for more than 100,000 deaths annually. representing about 5% of all deaths in the United States. Fetal alcohol syndrome is the third leading cause of birth defects with accompanying mental retardation (Michigan society for medical research, 2003). Acute and chronic alcoholism carry the potential to damage many organs of the body. including the heart. brain. liver, kidney, digestive system and reproductive system (erectile dysfunction and cessation of menstruation). When alcohol was given. its level in the body increased and produced the intoxication effects. The undesirable toxic effects include damage of Leydig cells and spermatogenic lineage cells (Michigan society for medical research, 2003). Zinc is essential for normal growth and reproduction and it has a beneficial effect on the process of tissue repair and wound healing (King, 1990). Zinc is a constituent of antioxidant. superoxide disrnutase. It is also needed for proper maintenance of vitamin E level in the blood and aids in the absorption of vitamin A (Bert and Falchuk, 1993). It exerts a protective effect and possibly preventing cellular damage caused by oxidative stress (Marchesini et aI., 1996). | ||||
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