Phytochemical investigation of Salsola kali extract | ||||
| Records of Pharmaceutical and Biomedical Sciences | ||||
| Article 8, Volume 1, Issue 1, March 2017, Page 70-72 PDF (660.12 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/rpbs.2018.5921 | ||||
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| Authors | ||||
Tariq Alturkistani1; Marwan Bin Afif1; Rashed Alzahrani1; Reef Alnouno1; Jihan M. Badr  2
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| 1Department of Natural Products and Alternative Medicine, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia | ||||
| 2Department of Pharmacognosy, Faculty of Pharmacy, Suez Canal University, Ismailia, 41522, Egypt | ||||
| Abstract | ||||
| The present study focuses on biologically guided fractionation of the extract of Salsola kali, aiming to investigate its anti-inflammatory constituents. The total methanol together with petroleum ether, chloroform and ethyl acetate extracts were investigated for anti-inflammatory activity using rat paw edema test. Petroleum ether extract demonstrated the highest activity (60%) relative to the reference indomethacin. Accordingly, the petroleum ether extract was fractionated using different chromatographic techniques to afford finally 4 compounds identified as lupeol, β-sitosterol, ursolic acid and β-sitosterol-3-O-glucoside. | ||||
| Keywords | ||||
| Salsola kali; Anti-inflammatory; Rat paw edema; NMR | ||||
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