“ROLE OF UTERINE ARTERY DOPPLER AND LATE FIRST TRIMESTER MATERNAL SERUM PREGNANCY_ASSOCIATED PLASMA PROTEIN A IN PREDICTION OF PREECLAMPSIA”
khallaf, A., elkholy, G., elsaid, M., rafea, A. (2019). “ROLE OF UTERINE ARTERY DOPPLER AND LATE FIRST TRIMESTER MATERNAL SERUM PREGNANCY_ASSOCIATED PLASMA PROTEIN A IN PREDICTION OF PREECLAMPSIA”. EKB Journal Management System, 36(1), 1-30. doi: 10.21608/bmfj.2019.15265.1027
amira magdy khallaf; galal elkholy; mostafa elsaid; ahmed rafea. "“ROLE OF UTERINE ARTERY DOPPLER AND LATE FIRST TRIMESTER MATERNAL SERUM PREGNANCY_ASSOCIATED PLASMA PROTEIN A IN PREDICTION OF PREECLAMPSIA”". EKB Journal Management System, 36, 1, 2019, 1-30. doi: 10.21608/bmfj.2019.15265.1027
khallaf, A., elkholy, G., elsaid, M., rafea, A. (2019). '“ROLE OF UTERINE ARTERY DOPPLER AND LATE FIRST TRIMESTER MATERNAL SERUM PREGNANCY_ASSOCIATED PLASMA PROTEIN A IN PREDICTION OF PREECLAMPSIA”', EKB Journal Management System, 36(1), pp. 1-30. doi: 10.21608/bmfj.2019.15265.1027
khallaf, A., elkholy, G., elsaid, M., rafea, A. “ROLE OF UTERINE ARTERY DOPPLER AND LATE FIRST TRIMESTER MATERNAL SERUM PREGNANCY_ASSOCIATED PLASMA PROTEIN A IN PREDICTION OF PREECLAMPSIA”. EKB Journal Management System, 2019; 36(1): 1-30. doi: 10.21608/bmfj.2019.15265.1027

“ROLE OF UTERINE ARTERY DOPPLER AND LATE FIRST TRIMESTER MATERNAL SERUM PREGNANCY_ASSOCIATED PLASMA PROTEIN A IN PREDICTION OF PREECLAMPSIA”

Benha Medical Journal
Article 1, Volume 36, Issue 1, April 2019, Page 1-30  XML
Document Type: Original Article
DOI: 10.21608/bmfj.2019.15265.1027
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Authors
amira magdy khallaf email 1; galal elkholy2; mostafa elsaid3; ahmed rafea4
1obs & gyn faculty of medicine benha university in benha city
2obs & gyn department , faculty of medicine ,benha university,egypt
3obs & gyn department ,faculty of medicine ,benha university,egypt
4obs & gyn department ,faculty of medicine ,benha university
Abstract
background: PE with a high prevalence in the first pregnancy is associated with the highest maternal and foetal morbidity and mortality, The possibility of prediction of preeclampsia (PE) at 11-14 weeks of pregnancy is a fairly new concept in recent years,the objective of this study to assess role of uterine artery Doppler and late first trimester maternal serum pregnancy associated plasma protein A in early prediction of preeclampsia.
Material &Methods: prospective observational clinical study was done at the Department of Obstetrics & Gynecology , Benha university,with200 pregnant women attending OPD at 11-14 weeks of gestation,approved by IRP,blood pressure was recorded, uterine aretery Doppler was done, blood sample for PAPP-A was drawn, uterine artery Doppler pulsatility index (pI) at 11-14 weeks of pregnancy was found to be agood screening method for prediction of preeclampsia. The data was analyzed using STATA/SE version 11.2 statistical analysis software.
Results: uterine artery Doppler pulsatility index (pI) at 11-14 weeks of pregnancy was found to be agood screening method (sensitivity 87%, specificity 96%) for prediction of preeclampsia.Conclusion:This study concluded that uterine artery Doppler was good screening method at 11-14 weeks of gestation for prediction of development of pre-eclampsia & mean pulsatility index was more valid than PAPP-A in prediction of pre-eclampsia.
Key words: preeclampsia ,PAPP-A, uterine artery Doppler.
Abbreviations: preeclampsia (PE),pregnancy associated plasma protein –A ( PAPP-A), pulsatility index (pi) , outpatient department (OPD).
Keywords
preeclampsia; PAPP-A; uterine artery Doppler
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