Role of Complete Blood Picture in Predicting the Etiology of Extrahepatic Cholestasis | ||||
| The Medical Journal of Cairo University | ||||
| Article 19, Volume 86, December, December 2018, Page 3525-3532 PDF (713.57 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/mjcu.2018.60593 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| WAEL M. MORSY, M.Sc.; ESAM A. EL-BEIH, M.D.; MUHAMMAD A. EL-MASRY, M.D. | ||||
| The Department of Internal Medicine, Al-Eman General Hospital* and Faculty of Medicine, Assiut University Hospitals**,*** and Department of Tropical, Al-Rajhy Liver Hospital*** | ||||
| Abstract | ||||
| Abstract Background: Extrahepatic cholestasis is a common prob-lem worldwide and faced in daily practice however it's etiology has a wide range, before starting treatement it is mandatory to reach the cause of the disease. Investigative tools such as computerized tomography, magnetic resonance cholangiopan-creatography etc are expensive, not available in every centers, moreover their accuracy not reaching 100%. Aim of Study: To analyse the role of complete blood count parameters namely RDW, MPV, PDW, PCT, N/L ratio, P/L ratio which are cheap and already available in 1ry care centers in assessment of extrahepatic cholestasis. Patients and Methods: It is a cross-sectional comparative descriptive study conducted during a period of one year starting from 1/3/2016 to 28/2/2017 at Al-Rajhy Liver Hospital, Assiut University Hospitals, on patients presented with defin-itive evidence of extrahepatic cholestasis by clinical exami-nation, laboratory evidence and trans-abdominal ultrasonog-raphy. Results: Thirty eight patients having extrahepatic cholesta-sis were included in the final analysis with a mean age of 47 years of them 14 patients were male. And 10 cases were taken as a control group of them 6 cases were male. Comparing between different etiological types of extrahepatic cholestasis as regards six parameters of the complete blood pictures namely RDW, MPV, PDW, PCT, N/L ratio, P/L ratio shows no significant differences between them. But MPV and PDW were significantly elevated in malignant distal group than control group. Conclusion: Complete blood count parameters namely RDW, MPV, PDW, PCT, N/L ratio, P/L ratio have no significant role in the differentiation between different etiologies of extrahepatic cholestasis. But MPV and PDW were significantly elevated in malignant distal extrahepatic cholestasis than cases without hyperbilirubinemia. | ||||
| Keywords | ||||
| Extrahepatic cholestasis – Complete blood count – Malignant – Calcular | ||||
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