Morphea patients treated with platelet rich plasma:a pilot study
Ibrahim, S., Khashaba, S., elhanfi, A. (2022). Morphea patients treated with platelet rich plasma:a pilot study. EKB Journal Management System, 28(6.2), 40-44. doi: 10.21608/zumj.2019.18752.1604
samia Ali Ibrahim; Shrook Khashaba; amira elhanfi. "Morphea patients treated with platelet rich plasma:a pilot study". EKB Journal Management System, 28, 6.2, 2022, 40-44. doi: 10.21608/zumj.2019.18752.1604
Ibrahim, S., Khashaba, S., elhanfi, A. (2022). 'Morphea patients treated with platelet rich plasma:a pilot study', EKB Journal Management System, 28(6.2), pp. 40-44. doi: 10.21608/zumj.2019.18752.1604
Ibrahim, S., Khashaba, S., elhanfi, A. Morphea patients treated with platelet rich plasma:a pilot study. EKB Journal Management System, 2022; 28(6.2): 40-44. doi: 10.21608/zumj.2019.18752.1604

Morphea patients treated with platelet rich plasma:a pilot study

Zagazig University Medical Journal
Article 8, Volume 28, Issue 6.2, November 2022, Page 40-44  XML PDF (370.56 K)
Document Type: Original Article
DOI: 10.21608/zumj.2019.18752.1604
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Authors
samia Ali Ibrahim1; Shrook Khashabaorcid 2; amira elhanfi email 3
1Dermatology, Venereology and Andrology, Faculty of Medicine, Zagazig University, Zagazig, Egypt
2Dermatology, Venereology and Andrology Department, faculty of Medicine, Zagazig University
3dermatology department, el ahrar teaching hospital, zagazig, egypt
Abstract
Background: There are multiple treatment options for morphea, but all have limited success or a wide range of side effects. Platelet-rich plasma is an innovative type of contour defect therapy, with long-lasting morphea, good cosmetic outcomes and limited side effects. Aim: To assess clinically the effect of PRP in the treatment of patients with morphea. Methods: A pilot study conducted on five morphea patients were recruited for this study. Intradermal platelet rich plasma was injected into morphea plaques once weekly for 12 sessions. The disease severity and damage were evaluated at the first visit and after the last session using the Localized Scleroderma Assessment Tool. Results: After 12 sessions, one case showed significant improvement, three cases showed partial improvement and one showed no response. The modified Localized Skin Severity Index and Localized Scleroderma Damage Index were significantly reduced after treatment. Patients with short disease duration (< 1 year) showed better response. Conclusion: Platelet rich plasma is a successful option for patients with localized types of morphea with good cosmetic outcome and minimal side effects.
Key words: morphea, platelet-rich plasma, cosmetic outcome.
Keywords
morphea; platelet-rich plasma; cosmetic outcome
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