Vitamin D Status and Spontaneous Intra Cerebral Hemorrhage: Would it be Able to Help? | ||||
| The Medical Journal of Cairo University | ||||
| Article 60, Volume 86, December, December 2018, Page 3863-3872 PDF (734 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/mjcu.2018.61857 | ||||
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| Authors | ||||
| ABEER A. TONY, M.D.; EFFAT A. TONY, M.D.; EMAD F. KHOLEF, M.D.; WAFAA S. MOHAMMED, M.D. | ||||
| The Departments of Neurology*, Internal Medicine** and Clinical Pathology***, Faculty of Medicine, Aswan*,*** and Assiut** Universities, Egypt | ||||
| Abstract | ||||
| Abstract Background: Vitamin D deficiency has in like manner rose as a hazard factor for cerebrovascular stroke. It is ques-tionable if vitamin D status impacts the anticipation of patients who have created intracerebral hemorrhage. In Aswan gov-ernate, most of people had low vitamin D levels in spite of its sunny weather, as well as increased number of hemorrhagic stroke. Aim of Study: Consequently, our study planned to look at the connection between serum 25 (OH) D status and hem-orrhagic stroke, to clear up their relationship with stroke seriousness, and to evaluate its connection with functional outcome and mortality in our considered patients. Patients and Methods: This prospective cross sectional study directed on 125 patients with first time acute stroke with spontaneous intracerebral hemorrhage. All members exposed to full history taking, detailed clinical examination and neurological checking. Brain imaging was performed after hospital admission. Blood tests were drawn for appraisal of serum 25-hydroxyl vitamin D and parathyroid hormone on the first day of admission. Results: 44% and 40% of examined patients with intrac-erebral hemorrhage had lacking and inadequate vitamin D levels respectively. There was a relationship between intrac-erebral hemorrhage with vitamin D levels, and the severity of the stroke and functional outcome. In dead patients with intracerebral hemorrhage, a low vitamin D level was detectable. Conclusion: Vitamin D deficiency may have a relationship with acute intracerebral hemorrhage and its pervasive hazard factors among individuals in Upper Egypt (Aswan). Low levels of vitamin D are freely prescient for deadly strokes with more confirmation of negative result in acute intracerebral hemorrhage. Consequently, It may be a marker of more noteworthy comorbidity and a being causally identified with stroke proposing that vitamin D supplementation is a promising approach in the preventive action of strokes. Further studies are needed to investigate this relationship among different territories of Egypt and for stroke subtypes. | ||||
| Keywords | ||||
| Acute stroke – Scandinavian Stroke Scale (SSS) – Modified Rankin Scale (mRS) – Serum 25- hydroxyvitamin D – Parathyroid hormone (PTH) | ||||
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