DETECTION OF EXTENDED-SPECTRUM -LACTAMASE ENZYMES (ESBLs) PRODUCED BY ESCHERICHIA COLI URINARY PATHOGENS AT ASSIUT UNIVERSITY HOSPITAL | ||||
Bulletin of Pharmaceutical Sciences Assiut University | ||||
Article 1, Volume 34, Issue 2, 2011, Page 93-103 PDF (801.6 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/bfsa.2011.63247 | ||||
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Authors | ||||
Amany G. Thabit1; Tharwat R. El-Khamissy2; Maggie A. Ibrahim1; Adel E. Attia2 | ||||
1Department of Microbiology and Immunology, Faculty of Medicine, Assiut University | ||||
2Department of Microbiology, Faculty of Pharmacy, Al-Azhar University, Assiut | ||||
Abstract | ||||
This study was conducted to evaluate the rate of urinary tract infection at Assiut University Hospitals, and to determine the prevalence of extended-spectrum β-lactamase enzymes producing community- and hospital-acquired E. coli uropathogens at Urology Department in Assiut University Hospitals. Also, to perform the antimicrobial sensitivity testing for E. coli isolates to extended-spectrum cephalosporins according to CLSI. Phenotypic confirmatory tests (combined disc method, double disc diffusion method and ESBL-E-Test) were performed to test E. coli isolates for ESBL production and it was concluded that 30 (39.47%) of community isolates and 42 (70%) of nosocomial isolates were ESBLs producers. | ||||
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