Antidiabetic, Antihyperlipidemic and Antioxidant Activities of Acacia albida in Streptozotocin-induced Diabetes in Rats and its Metabolites | ||||
| Egyptian Journal of Chemistry | ||||
| Article 29, Volume 63, Issue 1, January 2020, Page 337-348 PDF (2.08 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/ejchem.2019.18863.2160 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
Ahmed H. Garra  1; Sayed A. Eltomy 2; Abdel-razik H. Aarrag 3; Nadia M. Ahmed4
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| 1Chemistry of Natural compounds, National Research Center, 12622 Dokki, Cairo, Egypt | ||||
| 2National Research center Tanning lab. | ||||
| 3Pathology and Medical, National Research Center | ||||
| 44Biochemistry Departments, National Research Center | ||||
| Abstract | ||||
| The particular purpose of this research was to assess the antidiabetic, antihyperlipidemic and antioxidant activities of Acacia albdia methanol extract. In addition, a phytochemical study for A. albdia has been performed. Isolation and identification of pure compounds were carried out by different chromatographic and spectroscopic techniques. Quercetin, kaempferol and their glycosides have been isolated from A. albida leaves. Structures of the isolated compounds have been estimated by 1D/2D 1H/13C-NMR spectroscopy. Methanolic extract of the leaves of A. albida improved the diabetes status, and it showed antidiabetic, antihyperlipidimic and antioxidant effects. These findings suggest that A. albida leaves may be used as hypolipidemic and normo-glycemic agents, additionally; A. albida is a rich source of phenolic compounds | ||||
| Keywords | ||||
| Acacia albida; antidiabetic; Antihyperlipidimic; antioxidant; triglycerides | ||||
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