ISOLATION AND IDENTIFICATION OF ADIPOSE TISSUE-DERIVED STEM CELLS | ||||
| Biochemistry Letters | ||||
| Article 10, Volume 8, Issue 1, 2012, Page 225-231 PDF (374.78 K) | ||||
| DOI: 10.21608/blj.2012.64273 | ||||
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| Authors | ||||
| Zahran F.M.1; EL-Deen. I.M2; Salama. M3; Lotfy. A2 | ||||
| 1Biochemistry Division, Dept. of Chemistry, Faculty of Science, Zagazig University | ||||
| 2Faculty of Science, Port said University | ||||
| 3Faculty of Medicine, Mansoura University. | ||||
| Abstract | ||||
| Stem cells are considered new promising tool for treating many disorders. However, the difficulties in isolation of stem cells, the immunorejection problems and the ethical debates about their sources could slow down the progress in their application in clinical trials. In the present study we were able to isolate mesenchymal stem cells from adipose tissue. This would overcome the difficult isolation from elsewhere, the immunorejection problems (as they can be isolated from the same patient) and of course the ethical debate as they will be isolated form a known source after taking conste of the patient. The characterization of the isolated adipose tissue derived stem cells (ADSCs) revealed mesenchymal markers (CD29,90) and absence of Hematopoietic markers (CD45). So, these results support the capacity of adipose tissue to be an easy source for obtaining functional stem cells | ||||
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