Clinicopathological Studies on the Effect of Acidifier and Probiotics in Broilers
Abdalla, O., Moursi, M., Kilany, O., Dessouki, A., Ahmed, S. (2015). Clinicopathological Studies on the Effect of Acidifier and Probiotics in Broilers. EKB Journal Management System, 20(2), 1-21. doi: 10.21608/scvmj.2015.64554
Osama Abdalla; Mohamed Moursi; Omnia Kilany; Amina Dessouki; Shimaa Ahmed. "Clinicopathological Studies on the Effect of Acidifier and Probiotics in Broilers". EKB Journal Management System, 20, 2, 2015, 1-21. doi: 10.21608/scvmj.2015.64554
Abdalla, O., Moursi, M., Kilany, O., Dessouki, A., Ahmed, S. (2015). 'Clinicopathological Studies on the Effect of Acidifier and Probiotics in Broilers', EKB Journal Management System, 20(2), pp. 1-21. doi: 10.21608/scvmj.2015.64554
Abdalla, O., Moursi, M., Kilany, O., Dessouki, A., Ahmed, S. Clinicopathological Studies on the Effect of Acidifier and Probiotics in Broilers. EKB Journal Management System, 2015; 20(2): 1-21. doi: 10.21608/scvmj.2015.64554

Clinicopathological Studies on the Effect of Acidifier and Probiotics in Broilers

Suez Canal Veterinary Medical Journal. SCVMJ
Article 1, Volume 20, Issue 2, December 2015, Page 1-21  XML PDF (2.13 MB)
Document Type: Original Article
DOI: 10.21608/scvmj.2015.64554
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Authors
Osama Abdalla1; Mohamed Moursi* 2; Omnia Kilany3; Amina Dessouki4; Shimaa Ahmed5
1Dept of Clinical Pathology, Fac. Vet. Med., Suez Canal University
2National Laboratory for Veterinary Quality Control on Poultry Production, Ismailia
3Dept of Clinical Pathology , Fac. Vet. Med., Suez Canal University.
4Dept of Pathology, Fac. Vet. Med., Suez Canal University.
5Dept of Clinical Pathology, Fac. Vet. Med., Suez Canal University.
Abstract
This study was conducted on 250 Cobb broilers, healthy chicks one- day- old, to evaluate and compare the impact of using water natural additives (such as acidifier and probiotics) on broiler. Complete blood pictures and immune response, as well as histopathological in treated and experimentally infected chickens with E.coli compared to control.The birds were randomly allotted to ten treatment groups (A - J). Control, probiotic (HerriC 20%) as 0.5 gm, 1gm / 4 liters of drinking water respectively, acidifier (AniGut) as at dose of 1 and 2 ml/ litre of drinking water respectively and another same treatment groups and infected with E coli O78 containing 4 x 106 colony-forming units CFU /ml in phosphate buffered saline (PBS) at 21 days of age. The result indicated that, probiotic treated groups ‘showed significant increase (P<0.05) in RBCs count and PCV value at 4 and 6 weeks, showed non-significant changes in Hb conc., MCV, MCH and MCHC in compare with the control, while acidifier treated groups showed non-significant changes in erythrogram. The leukogram studies revealed that, there was increase in TLC with characteristic heterophilia, lymphocytosis, and monocytosis in infected non treated group and in probiotic treated groups, while acidifier treated groups showed non-significant changes in TLC and D.L.C all over the experiment. The result of immunological parameters showed an elevation in the serum of IgG and IgM in infected group and in probiotic treated groups. While acidifier treated groups showed non-significant changes. The results of IL-6 and IL-12 showed that there were a significant increase in all infected groups and in probiotic treated groups, while acidifier treated groups showed non-significant changes. Histopathological results showed that addition of probiotic improved all the examined organs. The study concluded that Probiotic has marked growth promoter as well as immunomodulatory effects in broilers, the low dose of probiotic (0.5 gm) proved to be more beneficial than the higher dose.
Keywords
Acidifier; probiotics; Clinical pathology; Broilers
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