ANTIOXIDANT, HEPATOPROTECTIVE AND ANTIMICROBIAL ACTIVITIES OF THE AERIAL PARTS OF POLYGONUM BELLARDII All.
Abd El-Kader, A., Nafady, A., Ahmed, A., Ibraheim, Z. (2012). ANTIOXIDANT, HEPATOPROTECTIVE AND ANTIMICROBIAL ACTIVITIES OF THE AERIAL PARTS OF POLYGONUM BELLARDII All.. EKB Journal Management System, 35(1), 43-53. doi: 10.21608/bfsa.2012.64600
Adel M. Abd El-Kader; Alaa M. Nafady; Amany S. Ahmed; Zedan Z. Ibraheim. "ANTIOXIDANT, HEPATOPROTECTIVE AND ANTIMICROBIAL ACTIVITIES OF THE AERIAL PARTS OF POLYGONUM BELLARDII All.". EKB Journal Management System, 35, 1, 2012, 43-53. doi: 10.21608/bfsa.2012.64600
Abd El-Kader, A., Nafady, A., Ahmed, A., Ibraheim, Z. (2012). 'ANTIOXIDANT, HEPATOPROTECTIVE AND ANTIMICROBIAL ACTIVITIES OF THE AERIAL PARTS OF POLYGONUM BELLARDII All.', EKB Journal Management System, 35(1), pp. 43-53. doi: 10.21608/bfsa.2012.64600
Abd El-Kader, A., Nafady, A., Ahmed, A., Ibraheim, Z. ANTIOXIDANT, HEPATOPROTECTIVE AND ANTIMICROBIAL ACTIVITIES OF THE AERIAL PARTS OF POLYGONUM BELLARDII All.. EKB Journal Management System, 2012; 35(1): 43-53. doi: 10.21608/bfsa.2012.64600

ANTIOXIDANT, HEPATOPROTECTIVE AND ANTIMICROBIAL ACTIVITIES OF THE AERIAL PARTS OF POLYGONUM BELLARDII All.

Bulletin of Pharmaceutical Sciences Assiut University
Article 4, Volume 35, Issue 1, June 2012, Page 43-53  XML PDF (1.54 MB)
Document Type: Original Article
DOI: 10.21608/bfsa.2012.64600
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Authors
Adel M. Abd El-Kader1; Alaa M. Nafady1; Amany S. Ahmed2; Zedan Z. Ibraheim2
1Department of Pharmacognosy, Faculty of Pharmacy, Al-Azhar University, Assiut 71524, Egypt
2Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt
Abstract
The methanolic extract of Polygonum bellardii All. (flowering aerial parts) and its fractions in addition to the isolated compounds (1-6) showed significant antioxidant potential by DPPH • scavenging activity technique. It also showed hepatoprotective activity against carbon tetrachloride (CCl4) induced hepatic injury in albino rats. The fractions exhibited antibacterial activity against both Gram positive and Gram negative bacteria in addition to antifungal activity. The total methanolic extract of Polygonum bellardii All. did not show signs of toxicity and mortality up to 4 g/kg dose. Determination of total flavonoid content with respect to quercetin spectrophotometrically indicated the presence of 185.2±1.03 mg/g dried extract.
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