Topical Bromfenac combined with prednisolone versus topical prednisolone in the management of pseudophakic cystoid macular oedema
Albialy, H., Gouda, D., Wagih, M. (2023). Topical Bromfenac combined with prednisolone versus topical prednisolone in the management of pseudophakic cystoid macular oedema. EKB Journal Management System, 29(1.1), 350-354. doi: 10.21608/zumj.2019.20440.1637
Hany Abdalhafiz Albialy; Doaa Mohammed Gouda; Mostafa Mohammed Wagih. "Topical Bromfenac combined with prednisolone versus topical prednisolone in the management of pseudophakic cystoid macular oedema". EKB Journal Management System, 29, 1.1, 2023, 350-354. doi: 10.21608/zumj.2019.20440.1637
Albialy, H., Gouda, D., Wagih, M. (2023). 'Topical Bromfenac combined with prednisolone versus topical prednisolone in the management of pseudophakic cystoid macular oedema', EKB Journal Management System, 29(1.1), pp. 350-354. doi: 10.21608/zumj.2019.20440.1637
Albialy, H., Gouda, D., Wagih, M. Topical Bromfenac combined with prednisolone versus topical prednisolone in the management of pseudophakic cystoid macular oedema. EKB Journal Management System, 2023; 29(1.1): 350-354. doi: 10.21608/zumj.2019.20440.1637

Topical Bromfenac combined with prednisolone versus topical prednisolone in the management of pseudophakic cystoid macular oedema

Zagazig University Medical Journal
Article 48, Volume 29, Issue 1.1, January 2023, Page 350-354  XML PDF (259.48 K)
Document Type: Original Article
DOI: 10.21608/zumj.2019.20440.1637
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Authors
Hany Abdalhafiz Albialy email orcid 1; Doaa Mohammed Goudaorcid 2; Mostafa Mohammed Wagihorcid 3
1Departmemt of ophthalmology,faculity of medicine , Zagazig university0000
2Zagazig ophthalmic hospital, Zagazig, Egypt
3Ophthalmology Department, Zagazig University, Zagazig, Egypt
Abstract
Abstract
Purpose:
To compare the efficacy of topical Bromfenac 0.09% combined with topical Prednisone acetate 1% versus topical Prednisilone alone in the management of pseudophakic cystoid macular oedema.
Methods:
Randomized comparative study included 20 eyes of 20 patients diagnosed with cystoid macular oedema following uncomplicated phacoemulsification . Ten eyes were received topical Bromfenac 0.09% combined with topical Prednisone acetate 1%. The other 10 eyes received only topical Prednisone acetate 1% . Follow up for three months by visual acuity assessment , slit lamp biomicroscopy and OCT macular scan.
Results:
Mean baseline BCVA in Group 1 was 0.65±0.23, and after 3 months = 0.35±0.21. The baseline mean visual acuity in group 2 were (0.75) ±0.19 , at the end of study visual acuity mean values were 0.35 ±0.21 . Baseline Mean macular thickness of Group was 381.3±72.3µ ,while the mean macular thickness of group 2 were (382) ± 115.7 µ .At the end of study mean macular thickness group was (307.2) ±67.5µ, while group 2 mean values were (356.1) ± 108.82µ .There was statistically significant difference in central macular thickness between baseline on one side and two and three months on the other side . Comparison of visual acuity between the two groups showed a statistically significant in two months only while there was no statistically significant difference in other time intervals.
Conclusion:
Bromfenac combined with topical Prednisone acetate significantly decreased macular thickness and improved visual acuity in cases with pseudophakic macular oedema compared to patients received topical Prednisone acetate only.
Keywords
Pseudophakic cystoid macular oedema; Irvin gas syndrome; Bromfenac 0.09%; Prednisone acetate1%; cataract surgery
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