SYNTHESIS AND ANTICONVULSANT ACTIVITY OF 1,3-DISUBSTITUTED 2,4(1H,3H)QUINAZOLINEDIONE | ||||
Bulletin of Pharmaceutical Sciences Assiut University | ||||
Article 7, Volume 28, Issue 1, June 2005, Page 45-56 PDF (273.14 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/bfsa.2005.65182 | ||||
View on SCiNiTO | ||||
Author | ||||
Abdel Ghany Ali El-Helby | ||||
Pharmaceutical Chemistry Department, Faculty of Pharmacy, Al-Azhar University, Cairo, Egypt | ||||
Abstract | ||||
Some new 2,4(1H,3H)-quinazolinedione were synthesized and characterized by elemental analysis, IR, 1HNMR and Ms spectral data. Pharmacological evaluation of some of the synthesized compounds as anticonvulsants showed that they displayed weak anticonvulsant activity relative to phenobarbitone sodium as reference drug. | ||||
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