XANTHONES FROM CELL CULTURES OF HYPERICUM GNIDIOIDES SEEM.
Abd El-Mawla, A. (2005). XANTHONES FROM CELL CULTURES OF HYPERICUM GNIDIOIDES SEEM.. EKB Journal Management System, 28(1), 105-111. doi: 10.21608/bfsa.2005.65249
A. M. A. Abd El-Mawla. "XANTHONES FROM CELL CULTURES OF HYPERICUM GNIDIOIDES SEEM.". EKB Journal Management System, 28, 1, 2005, 105-111. doi: 10.21608/bfsa.2005.65249
Abd El-Mawla, A. (2005). 'XANTHONES FROM CELL CULTURES OF HYPERICUM GNIDIOIDES SEEM.', EKB Journal Management System, 28(1), pp. 105-111. doi: 10.21608/bfsa.2005.65249
Abd El-Mawla, A. XANTHONES FROM CELL CULTURES OF HYPERICUM GNIDIOIDES SEEM.. EKB Journal Management System, 2005; 28(1): 105-111. doi: 10.21608/bfsa.2005.65249

XANTHONES FROM CELL CULTURES OF HYPERICUM GNIDIOIDES SEEM.

Bulletin of Pharmaceutical Sciences Assiut University
Article 17, Volume 28, Issue 1, June 2005, Page 105-111  XML PDF (196.9 K)
Document Type: Original Article
DOI: 10.21608/bfsa.2005.65249
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Author
A. M. A. Abd El-Mawla
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt
Abstract
Oxygenated and prenylated xanthones were isolated from the cell cultures of Hypericum gnidioides Seem. when grown in modified B5 medium in the dark. Based on the spectral methods, the structure of the isolated compounds were elucidated as 1,7-dihydroxyxanthone (euxanthone), 1,3,7-trihydroxyxanthone, 1,3,5,6-tetrahydroxyxanthone, 1,3,6,7-tetrahydroxy-8(3-methylbut-2-enyl) xanthone and 1,3,6,7-tetrahydroxy-2,8-di(3-methylbut-2-enyl) xanthone (  -mangostin). The occurrence of both 1,7-dihydroxyxanthone and 1,3,7- trihydroxyxanthone which is recorded for the first time in cell cultures of Hypericum species indicate the presence of a reductase activity responsible for eliminating the 3-hydroxy group and confirm the biosynthetic pathway of xanthones in Hypericum species respectively.
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