CHEMICAL CONSTITUENTS AND MOLLUSCICIDAL ACTIVITY OF IRIS PSEUDACORUS L. CULTIVATED IN EGYPT | ||||
| Bulletin of Pharmaceutical Sciences Assiut University | ||||
| Article 20, Volume 27, Issue 1, June 2004, Page 161-169 PDF (325.32 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/bfsa.2004.65438 | ||||
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| Authors | ||||
| H. G. Sary1; N A. Ayoub1; A. B. Singab* 1; A. H. Ahmed2; M. M. Al-Azizi1 | ||||
| 1Department of Pharmacognosy, Ain Shams University, Faculty of Pharmacy, Abbassia, Cairo, Egypt | ||||
| 2National Hepatology and Tropical Medicine Research Institute, General Organization of Teaching Hospitals and Institutes | ||||
| Abstract | ||||
| The molluscicidal activity of leaves and rhizomes extracts of Iris pseudacorus L. family Iridiaceae against Biomphalaria alexandrina snails were evaluated and proved activity. The successive extracts of leaves viz; n-hexane, chloroform, diethyl ether and ethyl acetate (LC50 values ranged from 0.8~14.65 mg/L) were found to be more potent than those of rhizomes. Bioactivity guided fractionation of leaves extracts resulted in the isolation of (13) compounds. The structural determination of the isolated compounds was established upon the study of their physicochemical and spectral data including UV, IR, 1H, 13C-NMR and MS as well as comparison with the data reported in literature. These compounds were identified as: apigenin (1), luteolin (2), -sitosterol-3-O-glucoside (3), catechol (4), protocatechuic acid (5), gallic acid (6), (-)-epicatechin (7), iso-vitexin (8), vitexin (9), iso-orientin (10), orientin (11), vicenin II (12) and mangiferin (13). Reviewing the available literature, this is the first report regarding the determination of molluscicidal activity as well as isolation and identification of these compounds from Iris pseudacorus L. | ||||
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