Phytochemical and biological studies on the leaves of Tecoma mollis Humb. And Bonpl cultivated in Egypt | ||||
Bulletin of Pharmaceutical Sciences Assiut University | ||||
Article 12, Volume 25, Issue 2, December 2002, Page 297-228 PDF (1.27 MB) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/bfsa.2002.65703 | ||||
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Authors | ||||
Nasr A. El-Emary; Azza A. Khalifa; Enaam Y. Backheet; Wael M. Abdel-Mageed | ||||
Department of Pharmacognosy, Faculty of Pharmacy, Assiut University, Assiut, Egypt | ||||
Abstract | ||||
α-Amyrin, 3-β-hydroxy-urs-12-ene-28-aldehyde, β-sitosterol, ursolic acid lactone, ursolic acid, 2-β,3-,β,19-α-trihydroxy-urs-12-ene-28-oic acid (2-tormentic acid), β-sitosterol-3-O-β-D-glucoside, apigenin-7-O-α-L-rhamnoside, apigenin-7-O-rutinoside, luteolin-7-O-rutinoside, and apigenin-6,8-di-C-β-D-glucopyranoside (vicenin 2) (11) were isolated for the first time fron an ethanolic ext. of the leaves of Tecoma mollis Humb and Bonpl. cultivated in Egypt. Identification of these compds. has been established by phys. and spectral data (UV, IR, MS, 1H- and 13C-NMR) as well as by comparison with authentic samples. Moreover, the biol. screening showed that the non polar fraction of the alc. ext. (n-hexane, chloroform), polar fraction (Et acetate, n-butanol) and aq. ext. as well as ursolic acid possess significant anti-inflammatory, analgesic and antipyretic activities. In addn., the polar fraction and aq. ext. possess also a significant anticonvulsant activity. | ||||
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