Peripheral Photon Doses from Different Techniques Delivered in Prostate Radiotherapy: Experimental Measurements and TPS Calculations.
Azab, H., Moussa, R., Kamaleldin, M. (2020). Peripheral Photon Doses from Different Techniques Delivered in Prostate Radiotherapy: Experimental Measurements and TPS Calculations.. EKB Journal Management System, 53(1), 67-75. doi: 10.21608/ajnsa.2019.13839.1222
Hala Azab; Ranya Moussa; Maha Kamaleldin. "Peripheral Photon Doses from Different Techniques Delivered in Prostate Radiotherapy: Experimental Measurements and TPS Calculations.". EKB Journal Management System, 53, 1, 2020, 67-75. doi: 10.21608/ajnsa.2019.13839.1222
Azab, H., Moussa, R., Kamaleldin, M. (2020). 'Peripheral Photon Doses from Different Techniques Delivered in Prostate Radiotherapy: Experimental Measurements and TPS Calculations.', EKB Journal Management System, 53(1), pp. 67-75. doi: 10.21608/ajnsa.2019.13839.1222
Azab, H., Moussa, R., Kamaleldin, M. Peripheral Photon Doses from Different Techniques Delivered in Prostate Radiotherapy: Experimental Measurements and TPS Calculations.. EKB Journal Management System, 2020; 53(1): 67-75. doi: 10.21608/ajnsa.2019.13839.1222

Peripheral Photon Doses from Different Techniques Delivered in Prostate Radiotherapy: Experimental Measurements and TPS Calculations.

Arab Journal of Nuclear Sciences and Applications
Article 7, Volume 53, Issue 1, January 2020, Page 67-75  XML PDF (619.74 K)
Document Type: Original Article
DOI: 10.21608/ajnsa.2019.13839.1222
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Authors
Hala Azab email 1; Ranya Moussa2; Maha Kamaleldin3
1Ionizing Radiation Metrology Lab., National Institute of Standards, Giza, Egypt.
2Radiation Therapy Department, Faculty of Medicine, Cairo University,Cairo, Egypt.
3Radiation Therapy Department, Faculty of Medicine, Cairo University, Cairo, Egypt.
Abstract
Advanced techniques and modalities in delivering radiotherapy improved the ability of delivering higher tumor doses while minimizing dose to the critical organs. The aim of this work is to determine experimentally out-of-field doses associated with these modern radiotherapy techniques for actual clinical case of prostate carcinoma and intercompare it with the treatment planning system (TPS) calculations. Three prostate treatment plans of the intensity-modulated radiation therapy (IMRT), RapidArc, and the Three-Dimensional Conformal Radiotherapy (3D-CRT) techniques were delivered to an anthropomorphic phantom using 6 MV photons beams produced from a UNIQUE linear accelerator. The out-of-field surface doses at various distances from the isocenter and peripheral doses to organs at risk (OARs) were measured using the thermoluminescent detectors (TLD-700) then compared to the calculated doses from the used commercial Eclipse TPS version 11. The two implemented algorithms in the Eclipse TPS (analytical anisotropic algorithm, AAA and the Acuros XB algorithm, AXB) underestimated the surface out-of-field doses by a maximum average deviation of 49% till the distance of 15 cm from the isocenter reported to the 3D-CRT technique. IMRT and RA techniques were more precise than 3D-CRT in tumor coverage and sparing of OARs but resulted in larger peripheral photon doses. RA technique has the advantage of less treatment time than IMRT technique and also produce less peripheral photon doses because it uses fewer monitor units. Our results show that although AXB algorithm is significantly faster in dose calculations than AAA algorithm especially in modern techniques, but less accurate in estimating the out-of-field doses.
Keywords
Out-of-field doses; TLD-700; AAA algorithm; AXB algorithm; Prostate Cancer
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