Chemical and biological studies of Sinapis arvensis growing in Egypt

Ali, A. A.; Hassanean, H. A.; Mohammed, M.; Kamel, M. S.; El-Khayat, E. S.

doi:10.21608/bfsa.2000.66323

	Chemical and biological studies of Sinapis arvensis growing in Egypt
Bulletin of Pharmaceutical Sciences Assiut University
Article 2, Volume 23, Issue 2, December 2000, Page 99-109 PDF (2.81 MB)
Document Type: Original Article
DOI: 10.21608/bfsa.2000.66323
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Authors
A. A. Ali¹; H. A. Hassanean¹; M. Mohammed²; M. S. Kamel¹; E. S. El-Khayat²
¹Department of Pharmacognosy, Faculty of Pharmacy, Assiut University Assiut 71526, Egypt
²Department of Pharmacognosy, Faculty of Pharmacy, Al-Azhar University, Assiut 71524, Egypt
Abstract
From the Et acetate fraction of the alc. ext. of the flowers of Sinapis arvensis L. a new compd. given the name: (2,2'-diacetyloxy-3,3'-dihydroxy)-1,1'-dipropylether. In addn., three flavonoidal glycosides were also isolated and identified as: kaempferol-3-O-β-glucopyranoside, isorhamnetin-3,7-O-β-diglucopyranoside and isorhamnetin-3-O-β-glucopyranoside-7-O-α-rhamnopyranoside. Meanwhile the chloroform fraction of the alc. ext. of the seeds afforded β-amyrin, β-sitosterol, β-sitosterol-3-O-β-glucopyranoside and syringin. The GC/MS anal. of the fixed oil of the seeds revealed the presence of 14 fatty acids including a high percent (11.56%) of harmful erucic acid. The identification of the isolated compds. was based on different methods of phys., chem. and spectral anal. Moreover the biol. screening showed that the alc. ext. of the leaf, the flavonoids of the flower and to a lesser extent the oil of the seed possesses a significant antimicrobial activity, while the flavonoids of the flower showed a significant anti-inflammatory activity. In addn., the oil of the seed showed insignificant diuretic activity.


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