Comparative Phytochemical and Biological Study for Mesembryanthemum Nodiflorum and Aptenia Cordifolia Plants Growing in Egypt
El Hawary, S., Hassan, M., Mostafa, D., AbouZid, S., Sleem, A., Mohammed, R. (2020). Comparative Phytochemical and Biological Study for Mesembryanthemum Nodiflorum and Aptenia Cordifolia Plants Growing in Egypt. EKB Journal Management System, 63(7), 2509-2522. doi: 10.21608/ejchem.2020.20877.2248
Seham Salah Eldin El Hawary; Marwa Hassan; Dina Mostafa; Sameh AbouZid; Amany Sleem; Rabab Mohammed. "Comparative Phytochemical and Biological Study for Mesembryanthemum Nodiflorum and Aptenia Cordifolia Plants Growing in Egypt". EKB Journal Management System, 63, 7, 2020, 2509-2522. doi: 10.21608/ejchem.2020.20877.2248
El Hawary, S., Hassan, M., Mostafa, D., AbouZid, S., Sleem, A., Mohammed, R. (2020). 'Comparative Phytochemical and Biological Study for Mesembryanthemum Nodiflorum and Aptenia Cordifolia Plants Growing in Egypt', EKB Journal Management System, 63(7), pp. 2509-2522. doi: 10.21608/ejchem.2020.20877.2248
El Hawary, S., Hassan, M., Mostafa, D., AbouZid, S., Sleem, A., Mohammed, R. Comparative Phytochemical and Biological Study for Mesembryanthemum Nodiflorum and Aptenia Cordifolia Plants Growing in Egypt. EKB Journal Management System, 2020; 63(7): 2509-2522. doi: 10.21608/ejchem.2020.20877.2248

Comparative Phytochemical and Biological Study for Mesembryanthemum Nodiflorum and Aptenia Cordifolia Plants Growing in Egypt

Egyptian Journal of Chemistry
Article 9, Volume 63, Issue 7, July 2020, Page 2509-2522  XML PDF (1.7 MB)
Document Type: Original Article
DOI: 10.21608/ejchem.2020.20877.2248
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Authors
Seham Salah Eldin El Hawaryorcid 1; Marwa Hassanorcid 2; Dina Mostafaorcid 3; Sameh AbouZidorcid 4; Amany Sleem5; Rabab Mohammed email orcid 6
1Pharmacognosy Department, Faculty of Pharmacy, Cairo University,Cairo, Egypt
2Pharmacognosy department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt
3Pharmacognosy Department, Faculty of Pharmacy, Misr University For Science and Technology
4Pharmacognosy Department, Faculty of Pharmacy, Heliopolis University, Cairo, Egypt.
5Pharmacology Department, National Research Centre, Dokki, Giza, Egypt
6Beni-Suef University Beni-Suef Uni
Abstract
In this work, Evaluation of the biological activity and the chemical composition of Mesembryanthemum nodiflorum and Aptenia cordifolia growing in Egypt were carried out. The chemical composition of both plants was evaluated by GC/MS and HPLC/MS analysis. GC/MS analysis of the unsaponifiable matter of Mesembryanthemum nodiflorum and Aptenia cordifolia resulted in the identification of 17 and 13 compounds; respectively, the major compounds were octadecane and neophytadiene; respectively. GC/MS analysis of the saponifiable matter of Mesembryanthemum nodiflorum and Aptenia cordifolia resulted in the identification of 12 and 18 compounds; respectively. The palmitic acid was the most abundant saturated fatty acid in both species. HPLC/MS analysis of Mesembryanthemum nodiflorum and Aptenia cordifolia resulted in the identification of 36 and 48 compounds; respectively. Finally biological studies indicated that the extract of Mesembryanthemum nodiflorum has more potent analgesic effect and also showed significant inhibitory activity against colon, cervix, liver and normal melanocyte carcinoma. The 70% ethanol extracts of the aerial parts of plants under investigation have a significant hypoglycemic effect, anti-oxidant, anti-inflammatory and hepatoprotective activity; where Aptenia cordifolia extract was more potent than Mesembryanthemum nodiflorum extract.
Keywords
Mesembryanthemum nodiflorum; Aptenia cordifolia; HPLC/MS; GC/MS; biological studies
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