Predictors of Complications After Flap Reconstruction of Oral Cavity Defects Following Ablation of Squamous Cell Carcinoma
Rayan, Y., Khairallah, S., Mousa, A., Alsharkawy, K., Kabbash, M. (2020). Predictors of Complications After Flap Reconstruction of Oral Cavity Defects Following Ablation of Squamous Cell Carcinoma. EKB Journal Management System, 78(1), 91-100. doi: 10.21608/ejhm.2020.67902
Yasser Mohammed Seddeik Abd El Raheim Rayan; Sherif Mohamed Khairallah; Ahmed K Mousa; Kamal Abdel Aal Mohamed Hassanein Alsharkawy; Mansour M Kabbash. "Predictors of Complications After Flap Reconstruction of Oral Cavity Defects Following Ablation of Squamous Cell Carcinoma". EKB Journal Management System, 78, 1, 2020, 91-100. doi: 10.21608/ejhm.2020.67902
Rayan, Y., Khairallah, S., Mousa, A., Alsharkawy, K., Kabbash, M. (2020). 'Predictors of Complications After Flap Reconstruction of Oral Cavity Defects Following Ablation of Squamous Cell Carcinoma', EKB Journal Management System, 78(1), pp. 91-100. doi: 10.21608/ejhm.2020.67902
Rayan, Y., Khairallah, S., Mousa, A., Alsharkawy, K., Kabbash, M. Predictors of Complications After Flap Reconstruction of Oral Cavity Defects Following Ablation of Squamous Cell Carcinoma. EKB Journal Management System, 2020; 78(1): 91-100. doi: 10.21608/ejhm.2020.67902

Predictors of Complications After Flap Reconstruction of Oral Cavity Defects Following Ablation of Squamous Cell Carcinoma

The Egyptian Journal of Hospital Medicine
Article 13, Volume 78, Issue 1, January 2020, Page 91-100  XML PDF (549.04 K)
Document Type: Original Article
DOI: 10.21608/ejhm.2020.67902
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Authors
Yasser Mohammed Seddeik Abd El Raheim Rayan email 1; Sherif Mohamed Khairallah2; Ahmed K Mousa3; Kamal Abdel Aal Mohamed Hassanein Alsharkawy4; Mansour M Kabbash5
1Department of Maxillofacial Surgery, Faculty of Medicine, Aswan University
2Department of Oncosurgery, National Cancer Institute, Cairo University
3Department of Plastic Surgery, Faculty of Medicine, Aswan University
4Department of Maxillofacial, Head and Neck Surgery, Faculty of Medicine, Sohag University
5Department of General Surgery, Faculty of Medicine, Aswan University
Abstract
Background: Head and neck cancers represent the sixth most common cancer worldwide with an incidence of over 600,000 new cases per year. More than 90% of head and neck cancers are squamous cell carcinomas (SCC) that arise from the mucosal surfaces of the oral cavity, oropharynx and larynx. Objective: The aim of the current work was to investigate the predictors of complications after flap reconstruction of oral cavity defects following ablation of squamous cell carcinoma. Patients and methods: This prospective comparative study included a total of 41 patients who diagnosed to have oral SCCs, attending at the outpatient clinic of Head and Neck Surgery Unit, National Cancer Institute (NCI), Cairo University and Aswan University Hospital. Written informed consent of all the subjects was obtained after explaining the benefits and hazards for each method step. This study was conducted between 2015 to 2018. Approval of the ethical committee was obtained. Results: Patients with positive history of neoadjuvant chemoradiotherapy (CRTH) are 52% less likely to developing complications than those with negative history of neoadjuvant CRTH. Detection of the short-term oncologic outcome; in the 4 flaps was better in contralateral submental island flap (CSMIF) cases than others. CSMIF were found to be 58% less liable for recurrence in comparison with pectoralis major myocutaneous flap (PMMCF) that was why it didn't show any clinical or radiologically detectable recurrence within the period of 24 months postoperatively. Thoracodorsal artery perforator (TDAP) flaps were 2.6 times more liable for recurrence in comparison with PMMCF. RFFF flaps were found to be 1.2 times more liable for recurrence in comparison with PMMCF. Conclusion: The chosen 4 flaps for this study are applicable to be used for post ablative oral cavity reconstruction. Our flaps were equal in suitability for defect coverage (50-60%).
Keywords
Flap reconstruction; Oral cavity; Squamous cell carcinoma; PMMCF; CSMIF; RFFF; TDAP
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