STUDY OF THE SAPONIN CONTENT OF ATRIPLEX STYLOSA VIV. AND ITS MOLLUSCICIDAL EFFECT | ||||
| Bulletin of Pharmaceutical Sciences Assiut University | ||||
| Article 12, Volume 21, Issue 2, December 1998, Page 237-243 PDF (499.33 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/bfsa.1998.67986 | ||||
 View on SCiNiTO | ||||
| Author | ||||
| Mortada M. El-Sayed | ||||
| Laboratory of Medicinal Chemistry, Theodor Bilharz Research Institute, Imbaba, Giza, Egypt | ||||
| Abstract | ||||
| From the aerial parts of Atriplex stylosa Viv, four triterpenoidal saponins have been isolated. Their structures were established as 3-O-a-L-rhamnopyranosyl-(1®3)-b-D-glucuronopyranosyl hederagenin; 3-O-b-D-glucopyranosyl-(1®3)-b-D-glucuronopyranosyl hederagenin; 3-O-a-L-rhamnopyranosyl-(1®3)-b-D-glucuronopyranosyl hederagenin; 28-O-b-D-glucopyranoside and 3-O-a-L-rhamnopyranosyl-(1®)-[b-D-glucopyranosyl-(1®2)]-b-D-glucuronopyranosly oleanolec acid by spectroscopic methods (IR, 1H-NMR, 13C-NMR and FAB-MS) as well as on basis of acidic and alkaline hydrolysis. The three monodesmosidic saponins exhibited various molluscicidal activities against the two aquatic snails; Biomphalaria alexandrina and Lymnaea cailliaudi, the intermediate hosts of Schistosoma mansoni and Fasciola gigantica respectively in Egypt whereas the bidesmosidic saponin was inactive against the two snail species. | ||||
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