Synthesis of Novel N- and C-acyclic Nucleosides Derived from 2-hydrazino-6-methyluracil
Abd El Salam, H., Gaafar, A. (2020). Synthesis of Novel N- and C-acyclic Nucleosides Derived from 2-hydrazino-6-methyluracil. EKB Journal Management System, 63(7), 2775-2781. doi: 10.21608/ejchem.2020.21459.2279
Hayam A. Abd El Salam; A.M. Gaafar. "Synthesis of Novel N- and C-acyclic Nucleosides Derived from 2-hydrazino-6-methyluracil". EKB Journal Management System, 63, 7, 2020, 2775-2781. doi: 10.21608/ejchem.2020.21459.2279
Abd El Salam, H., Gaafar, A. (2020). 'Synthesis of Novel N- and C-acyclic Nucleosides Derived from 2-hydrazino-6-methyluracil', EKB Journal Management System, 63(7), pp. 2775-2781. doi: 10.21608/ejchem.2020.21459.2279
Abd El Salam, H., Gaafar, A. Synthesis of Novel N- and C-acyclic Nucleosides Derived from 2-hydrazino-6-methyluracil. EKB Journal Management System, 2020; 63(7): 2775-2781. doi: 10.21608/ejchem.2020.21459.2279

Synthesis of Novel N- and C-acyclic Nucleosides Derived from 2-hydrazino-6-methyluracil

Egyptian Journal of Chemistry
Article 29, Volume 63, Issue 7, July 2020, Page 2775-2781  XML PDF (1.34 MB)
Document Type: Original Article
DOI: 10.21608/ejchem.2020.21459.2279
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Authors
Hayam A. Abd El Salamorcid 1; A.M. Gaafar email 2
1Green Chemistry Department, National Research Centre, 33 EL Bohouthst. (former EL Tahrirst.) – Dokki – Giza – Egypt - P.O.12622.
2Department of Photochemistry,National Research Centre, 33 EL Bohouthst. (former EL Tahrirst.) – Dokki – Giza – Egypt - P.O.12622
Abstract
The reaction of 2-hydrazino-6-methyl uracil with different aldo- sugars yields the corresponding N-acyclic glycosides. However, some of them have cyclized successfully to form a new fused triazole ring. Apparently, such cyclization depends upon the Stereochemistry of the N-glycoside intermediates that produce the C-glycosides.”
Keywords
Uracil; N-glycoside; C-glycoside; acyclic nucleoside
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