MOLLUSCICIDAL SPIROSTANOL SAPONINS FROM AGAVE HETERACANTHA
El-Sayed, M. (1997). MOLLUSCICIDAL SPIROSTANOL SAPONINS FROM AGAVE HETERACANTHA. EKB Journal Management System, 20(2), 147-153. doi: 10.21608/bfsa.1997.68754
Mortada M. El-Sayed. "MOLLUSCICIDAL SPIROSTANOL SAPONINS FROM AGAVE HETERACANTHA". EKB Journal Management System, 20, 2, 1997, 147-153. doi: 10.21608/bfsa.1997.68754
El-Sayed, M. (1997). 'MOLLUSCICIDAL SPIROSTANOL SAPONINS FROM AGAVE HETERACANTHA', EKB Journal Management System, 20(2), pp. 147-153. doi: 10.21608/bfsa.1997.68754
El-Sayed, M. MOLLUSCICIDAL SPIROSTANOL SAPONINS FROM AGAVE HETERACANTHA. EKB Journal Management System, 1997; 20(2): 147-153. doi: 10.21608/bfsa.1997.68754

MOLLUSCICIDAL SPIROSTANOL SAPONINS FROM AGAVE HETERACANTHA

Bulletin of Pharmaceutical Sciences Assiut University
Article 5, Volume 20, Issue 2, December 1997, Page 147-153  XML PDF (471.33 K)
Document Type: Original Article
DOI: 10.21608/bfsa.1997.68754
View on SCiNiTO View on SCiNiTO
Author
Mortada M. El-Sayed
Laboratory of Medicinal Chemistry, Theodor Bilharz Research Institute, Imbaba, Giza, Egypt
Abstract
Four spirostanol saponin glycosides were isolated from the butanol fraction of the methanolic extract of the leaves of Agave heteracantha (Agavaceae). The structures of these saponins were elucidated by a combination of spectroscopic analysis and hydrolysis followed by identification of both aglycones as tigogenin and gitogenin as well as the sugar moieties. The four saponins exhibited strong molluscicidal activites against Biomphalaria alexandrina (LC90 = 10, 15, 7 and 9 ppm) and Lymnaea cailliaudi (LC90 = 8, 13, 5 and 6 ppm), the intermediate hosts of Schistosoma mansoni and Fasciola gigantica in Egypt respectively.
Statistics
Article View: 77
PDF Download: 155