3-(ETHOXYCARBONYL)-2-METHYLPYRROLE-5-CARBOXALDEHYDE AS A VERSATILE SYNTHONE FOR POTENTIAL ANTIBACTERIAL AGENTS
Mokhtar, H., El-Sayed, O., El-Sabaeny, A. (1995). 3-(ETHOXYCARBONYL)-2-METHYLPYRROLE-5-CARBOXALDEHYDE AS A VERSATILE SYNTHONE FOR POTENTIAL ANTIBACTERIAL AGENTS. EKB Journal Management System, 18(2), 59-67. doi: 10.21608/bfsa.1995.69684
Hassan M. Mokhtar; Ola A. El-Sayed; Azza H. El-Sabaeny. "3-(ETHOXYCARBONYL)-2-METHYLPYRROLE-5-CARBOXALDEHYDE AS A VERSATILE SYNTHONE FOR POTENTIAL ANTIBACTERIAL AGENTS". EKB Journal Management System, 18, 2, 1995, 59-67. doi: 10.21608/bfsa.1995.69684
Mokhtar, H., El-Sayed, O., El-Sabaeny, A. (1995). '3-(ETHOXYCARBONYL)-2-METHYLPYRROLE-5-CARBOXALDEHYDE AS A VERSATILE SYNTHONE FOR POTENTIAL ANTIBACTERIAL AGENTS', EKB Journal Management System, 18(2), pp. 59-67. doi: 10.21608/bfsa.1995.69684
Mokhtar, H., El-Sayed, O., El-Sabaeny, A. 3-(ETHOXYCARBONYL)-2-METHYLPYRROLE-5-CARBOXALDEHYDE AS A VERSATILE SYNTHONE FOR POTENTIAL ANTIBACTERIAL AGENTS. EKB Journal Management System, 1995; 18(2): 59-67. doi: 10.21608/bfsa.1995.69684

3-(ETHOXYCARBONYL)-2-METHYLPYRROLE-5-CARBOXALDEHYDE AS A VERSATILE SYNTHONE FOR POTENTIAL ANTIBACTERIAL AGENTS

Bulletin of Pharmaceutical Sciences Assiut University
Article 1, Volume 18, Issue 2, December 1995, Page 59-67  XML PDF (406.25 K)
Document Type: Original Article
DOI: 10.21608/bfsa.1995.69684
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Authors
Hassan M. Mokhtar1; Ola A. El-Sayed2; Azza H. El-Sabaeny3
1Department of Chemistry, Faculty of Science, Alexandria University, Alexandria, Egypt
2Department of Botany and Microbiology, Faculty of Science, Alexandria University, Alexandria, Egypt
3Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt
Abstract
Reaction of 3-(ethoxycarbonyl)-2-methylpyrrole-5-carboxaldehyde with substituted thiosemicarbazides afforded the corresponding (thiocarbamoyl) hydrazones. The latter compounds underwent cyclization to thiazole, thiazolidinone, thiazinone and thiadizole derivatives under the proper reaction condition. All the prepared compounds were evaluated for this antimicrobial activity.
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