Isolated Antibody to Hepatitis B Core Antigen in Egyptian Patients with Chronic Hepatitis C Virus Infection | ||||
| Suez Canal University Medical Journal | ||||
| Article 2, Volume 13, Issue 1, March 2010, Page 7-10 PDF (2.06 MB) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/scumj.2010.69767 | ||||
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| Authors | ||||
| Nora F. Mahmoud1; Salah M. Abdalla1; Alaa El-Din S. Abd El-Hamid2 | ||||
| 1Department of Microbiology and Immunology, Faculty of Pharmacy, Suez Canal University | ||||
| 2Department of Clinical Pathology, Faculty of Medicine, Suez Canal University | ||||
| Abstract | ||||
| Background: occult hepatitis B virus (HBV) infection is characterized by the presence of HBV infection with undetectable hepatitis B surface antigen (HBsAg). Such infections have been reported to be common in patients with chronic hepatitis C virus (HCV) infection. Objective: this study investigates the prevalence of occult HBV infection in patients with chronic liver disease by HCV. Methods: in a cross sectional study, a toal of 3043 blood donors were screened in 2009 for the following viral markers: hepatitis C virus antibody (anti-HCV), hepatitis B surface antigen (HBsAg), and human immunodeficiency virus I/II (anti-HIV I/II). All samples negative for HBsAg and positive for anti_HCV were tested for the presence of anti-hepatitis B core antigen (anti_HBc). Results: one hundred and fort samples (4.6%) were positive for anti-HCV. Of these 140 cases, 36 (25.71%) were anti_BHc positive. Conclusion: occult hepatitis B infections occur frequently in patients with chronic hepatitis C liver disease. | ||||
| Keywords | ||||
| Occult hepatitis B; HBV; HCV; Coinfection, Prevalence | ||||
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