A PRELIMINARY INVESTIGATION OF FLAVANOLIGNANS OF SILYBUM MARIANUM (L) GEARTN FRUITS GROWING IN EGYPT | ||||
Bulletin of Pharmaceutical Sciences Assiut University | ||||
Article 3, Volume 15, Issue 1, 1992, Page 22-26 PDF (183.75 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/bfsa.1992.70209 | ||||
View on SCiNiTO | ||||
Authors | ||||
L. Dranik1; L. Dolganenko1; A. Grysodub1; M. Levin1; I. M. Eshami2 | ||||
1All-Union Research Institute of Drug Chemistry and Technology, Kharkov, USSR | ||||
2Department of Pharmacognosy, Faculty of Pharmacy, Tanta University, Tanta, Egypt | ||||
Abstract | ||||
The flavanolignans of the fruits were isolated by column chromatography and identified by TLC and HPLC in addition to m.p., ms, uv and optical rotation measurements. A comparative study by TLC and HPLC of the flavanolignans from the purple flowered and the white-flowered plants of Silybum marianum was performed. The major flavanolignans of the white flowered plants were identified as silybin, silychristin, silydianin and taxipholin. The major flovanolignans of purple-f lowered plants were found to be silybin, silichristin and taxipholin. | ||||
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