THE USE OF HPLC-CYCLOBOND COLUMN FOR QUANTITATIVE DETERMINATION OF ANTICATARRHAL TABLETS | ||||
Bulletin of Pharmaceutical Sciences Assiut University | ||||
Article 1, Volume 14, Issue 1, 1991, Page 1-5 PDF (225.29 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/bfsa.1991.70369 | ||||
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Authors | ||||
S. M. El-Gizawy1; A. N. Ahmed2; M. A. Makboul3 | ||||
1Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy Assiut University, Assiut, Egypt | ||||
2Department of Organic Pharmaceutical Chemistry, Faculty of Pharmacy Assiut University, Assiut, Egypt | ||||
3Department of Pharmacognosy, Faculty of Pharmacy Assiut University, Assiut, Egypt | ||||
Abstract | ||||
The utility of high performance liquid chromatography cyclobond-I column for the separation and analysis of paracetamol, phenylpropanolamine HCl and chlorpheniramine maleate in synthetic mixture was clearly demonstrated using mobile-phase methanol: phosphate buffer pH 7.0 (10:90), flow rate 0.8 ml min-1 and the detection was affected spectrophotometrically at 254 nm. Adequate sensitivity and an excellent' precision were obtained for the determination of the commercial dosage form. | ||||
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