THE UTILITY OF 1-CYANOACETYL-4-(4-ETHOXYPHENYL) THIO-SEMICARBAZIDE FOR SYNTHESIS OF PYRAZOLE, TRIAZOLE, THIAZOLE, PYRIDINE AND CHROMENE DERIVATIVES | ||||
Al-Azhar Bulletin of Science | ||||
Article 6, Volume 22, Issue 1-A, June 2011, Page 85-96 PDF (423.47 K) | ||||
Document Type: Original Article | ||||
DOI: 10.21608/absb.2011.7179 | ||||
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Authors | ||||
H. KH. THABET* 1; M. H. HELAL1; M. A. SALEM1; A. A. FARRAG2 | ||||
1Chemistry Department, Faculty of Science, Al-Azhar University, 11284 Nasr City, Cairo, Egypt | ||||
2Chemistry Department, Faculty of Science (Girls), Al-Azhar University, Nasr City, Cairo, Egypt | ||||
Abstract | ||||
The reaction of cyanoacetic acid hydrazide with 4-ethoxyphenylisothiocyanate gave the thiosemicarbazide derivative (3). The latter underwent a series of heterocyclization reactions when it reacts with either α-halo compounds, thioglycolic acid, acetylacetone, cinnamonitrile, or o-hydroxy aldehydes | ||||
Keywords | ||||
Thiosemicarbazide derivative; 1,2,4-triazoles; pyrazole; Thiazoles; tri-azolylthiazolone; Chromenes | ||||
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