Effect of Amindarone induced hyper thyriodism on bone remodeling process: histological and radiodensitometric analysis. (Experimental study in rats)
Aboulmagd, I., Kamel, S. (2019). Effect of Amindarone induced hyper thyriodism on bone remodeling process: histological and radiodensitometric analysis. (Experimental study in rats). EKB Journal Management System, 65(Issue 2 - April (Oral Medicine, X-Ray, Oral Biology & Oral Pathology)), 1149-1156. doi: 10.21608/edj.2019.72184
Inass Abdel Rahman Aboulmagd; Samah Mohamed Kamel. "Effect of Amindarone induced hyper thyriodism on bone remodeling process: histological and radiodensitometric analysis. (Experimental study in rats)". EKB Journal Management System, 65, Issue 2 - April (Oral Medicine, X-Ray, Oral Biology & Oral Pathology), 2019, 1149-1156. doi: 10.21608/edj.2019.72184
Aboulmagd, I., Kamel, S. (2019). 'Effect of Amindarone induced hyper thyriodism on bone remodeling process: histological and radiodensitometric analysis. (Experimental study in rats)', EKB Journal Management System, 65(Issue 2 - April (Oral Medicine, X-Ray, Oral Biology & Oral Pathology)), pp. 1149-1156. doi: 10.21608/edj.2019.72184
Aboulmagd, I., Kamel, S. Effect of Amindarone induced hyper thyriodism on bone remodeling process: histological and radiodensitometric analysis. (Experimental study in rats). EKB Journal Management System, 2019; 65(Issue 2 - April (Oral Medicine, X-Ray, Oral Biology & Oral Pathology)): 1149-1156. doi: 10.21608/edj.2019.72184

Effect of Amindarone induced hyper thyriodism on bone remodeling process: histological and radiodensitometric analysis. (Experimental study in rats)

Egyptian Dental Journal
Article 1, Volume 65, Issue 2 - April (Oral Medicine, X-Ray, Oral Biology & Oral Pathology), April 2019, Page 1149-1156  XML PDF (1.8 MB)
Document Type: Original Article
DOI: 10.21608/edj.2019.72184
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Authors
Inass Abdel Rahman Aboulmagd1; Samah Mohamed Kamel2
1Lecturer, Department of Oral Radiology, Faculty of Dentistry, Fayoum University
2Lecturer, Department of Oral Biology, Faculty of Dentistry, October University of Modern Sciences and Art
Abstract
Objectives: The aim of the study was to evaluate the effect of Amindarone drug alone and in combination with cabbige on bone methabolism on both histological and radiographical .
Subjects& Methods: 15 rats were allocated in three groups, in group (I) the rats received the amiodarone, group (II) rats received aminodarone and uncooked cabbage while group(III) serve as a control group, by the end of 13th week the rats were sacrified using an overdose of I.V. Phenobarbital.mandibles of the rats were subjected to histological and radiograghic examination .
Results: on the radiographic examination of the rats’ mandible in group I that received the Amiodaron the bone density showed decrease with average of( 601 ± 203) while in group II that received the Amiodaron and cabbages showed less decrease in bone density with average of
(730±160.4) than the control group (group III) that showed average of bone density of (830±139.5) there is a significant difference among the groups P<0.001.
Conclusion: Amiodarone drug induced the hyperthyroidism in rats treated for 13 weeks.
The use of un cooked cabbage decrease the changes in the bone in both histological and radiographic evaluations
Keywords
Amindarone; hyper thyriodism; Computed tomography; CT Bone density
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