Assessment of salivary and gingival crevicular fluid Periostin levels in chronic periodontitis patients before and after non-surgical periodontal therapy
Hussien, A., Maged, A. (2019). Assessment of salivary and gingival crevicular fluid Periostin levels in chronic periodontitis patients before and after non-surgical periodontal therapy. EKB Journal Management System, 65(Issue 2 - April (Oral Medicine, X-Ray, Oral Biology & Oral Pathology)), 1389-1395. doi: 10.21608/edj.2019.72563
Amal A. Hussien; Amira Maged. "Assessment of salivary and gingival crevicular fluid Periostin levels in chronic periodontitis patients before and after non-surgical periodontal therapy". EKB Journal Management System, 65, Issue 2 - April (Oral Medicine, X-Ray, Oral Biology & Oral Pathology), 2019, 1389-1395. doi: 10.21608/edj.2019.72563
Hussien, A., Maged, A. (2019). 'Assessment of salivary and gingival crevicular fluid Periostin levels in chronic periodontitis patients before and after non-surgical periodontal therapy', EKB Journal Management System, 65(Issue 2 - April (Oral Medicine, X-Ray, Oral Biology & Oral Pathology)), pp. 1389-1395. doi: 10.21608/edj.2019.72563
Hussien, A., Maged, A. Assessment of salivary and gingival crevicular fluid Periostin levels in chronic periodontitis patients before and after non-surgical periodontal therapy. EKB Journal Management System, 2019; 65(Issue 2 - April (Oral Medicine, X-Ray, Oral Biology & Oral Pathology)): 1389-1395. doi: 10.21608/edj.2019.72563

Assessment of salivary and gingival crevicular fluid Periostin levels in chronic periodontitis patients before and after non-surgical periodontal therapy

Egyptian Dental Journal
Article 24, Volume 65, Issue 2 - April (Oral Medicine, X-Ray, Oral Biology & Oral Pathology), April 2019, Page 1389-1395  XML PDF (325.35 K)
Document Type: Original Article
DOI: 10.21608/edj.2019.72563
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Authors
Amal A. Hussien1; Amira Maged2
1Lecturer, Oral Medicine & Periodontology Department, Faculty of Dentistry, Cairo University, Egypt.
2Associate Professor, Oral Medicine & Periodontology Department, Faculty of Dentistry, Cairo University, Egypt.
Abstract
Introduction: Periostin is a matricellular protein highly expressed by the fibroblasts in the periodontal ligament. It is entangled in the maintenance of periodontal integrity which is affected by periodontal disease.
Aim: this study aimed to compare both GCF and salivary periostin levels during periodontal disease to their levels after non- surgical periodontal therapy.
Subjects and methods: The present study was performed on a total of 30 subjects, 13 males and 17 females. The thirty selected participants were sampled at baseline and after receiving the non-surgical periodontal treatment.
Results: In GCF, there was a statistically significant (at P ≤ 0.05) increase in mean Periostin level after treatment. While in saliva, there was a statistically significant (at P ≤0.05) decrease in mean Periostin level after treatment.
Conclusion Our results suggested that GCF periostin level may be considered as a reliable marker in the evaluation of periodontal disease activity, while salivary periostin level could have a promising diagnostic potential. So, further investigations are recommended.
 
Keywords
Periostin; non-surgical periodontal treatment; saliva; gingival crevicular fluid
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