Long-term assessment of the salivary oxidative stress status during orthodontic treatment with fixed appliances | ||||
| Egyptian Dental Journal | ||||
| Article 10, Volume 65, Issue 4 - October (Orthodontics, Pediatric & Preventive Dentistry), October 2019, Page 3151-3157 PDF (252.57 K) | ||||
| Document Type: Original Article | ||||
| DOI: 10.21608/edj.2019.73992 | ||||
 View on SCiNiTO | ||||
| Authors | ||||
| Marwa Sameh Shamaa1; Mostafa Mohamed Mansour2 | ||||
| 1Lecturer of Orthodontics, Faculty of Dentistry, Mansoura University | ||||
| 2Lecturer of Clinical Pathology, Faculty of Medicine, Mansoura University | ||||
| Abstract | ||||
| Introduction: Saliva has been considered a valuable diagnostic tool for many disorders and diseases. Objective: The aim of this study was to assess some important biomarkers of oxidative stress in the saliva of patients undergoing fixed orthodontic treatment. Methods: A total of thirty three subjects (18 females and 15 males) in the age group of 15-18 years were enrolled in the study. The salivary samples were collected before fixed appliance placement, 6 months and 1 year after orthodontic treatment onset. Samples were investigated for measurement of malondialdehyde (MDA), nitric oxide (NO) and 8-hydroxydeoxyguanosine (8-OHdG) levels. Results: The salivary MDA, NO and 8-OHdG concentrations in the individuals treated with fixed orthodontic appliances did not show significant changes neither after 6 nor after 12 months of treatment compared to the basal values before treatment . Conclusion: Fixed orthodontic therapy for one year did not induce oxidative damage in the oral cavity. | ||||
| Keywords | ||||
| Fixed orthodontic treatment; saliva; Oxidative Stress; Reactive oxygen species | ||||
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